症状性颈动脉狭窄在脑保护装置下CAS治疗的疗效

Effect of CAS on Symptomatic Carotid Artery Stenosis Under Cerebral Protection Device

目的探讨症状性颈动脉狭窄在脑保护装置下颈动脉狭窄支架成形术(CAS)治疗的临床疗效。方法将梅州市人民医院收治的症状性颈动脉狭窄患者68例随机分为观察组与对照组,每组各34例。对照组实施药物治疗,观察组在此基础上实施脑保护装置下CAS治疗,比较两组疗效。结果观察组治疗后MTT指数低于对照组,CBF、CBV指数均高于对照组,两组比较差异有统计学意义(P<0.05)。观察组治疗后的颅外颈动脉平均狭窄率为(15.12±2.67)%,NIHSS评分为(4.35±0.42)分,MRS评分为(1.47±0.26)分,均低于对照组,两组比较差异有统计学意义(P<0.05)。结论脑保护装置下CAS治疗可有效减轻症状性颈动脉狭窄患者的颅外颈动脉狭窄情况,改善靶病变血管相关区域脑灌注,提高神经功能,临床良好,值得推荐。

Objective To investigate the clinical effect of symptomatic carotid artery stenosis under CAS.Methods 68 patients with symptomatic carotid stenosis treated in the hospital were divided into the observation group and the control group randomly,with 34 cases in each group.The control group were treated with drug treatment.On this basis,the observation group were treated with CAS under the brain protection device.The curative effect of the two groups was compared.Results The MTT index of the observation group was lower than that of the control group.The index of CBF and CBV was higher than that of the control group.There was statisti cally significant difference between the two groups(P<0.05).The average stenosis rate of the extracranial carotid artery(15.12±2.67)%,NIHSS score(4.35±0.42)and MRS score(1.47±0.26)were lower in the observation group than in the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion CAS therapy under brain protection device can effectively improve the cranial carotid artery stenosis in patients with symptomatic carotid stenosis,improve the cerebral perfusion in the area related to the target vessel,and improve the nerve function.It is worthy of recommendation.