盐酸氨溴索治疗老年慢阻肺合并肺部感染的效果分析

Effect of Ambroxol Hydrochloride in the Treatment of Elderly Patients with Chronic Obstructive Pulmonary Disease Complicated with Pulmonary Infection

目的对盐酸氨溴索治疗老年慢阻肺合并肺部感染的效果进行分析和研究。方法选择该院在2018年7月-2019年1月期间收治的70例老年慢阻肺合并肺部感染的患者作为研究对象,按照硬币法将患者随机划分为对照组和观察组,每组35例。对对照组患者应用常规治疗方式治疗,在对照组的基础上,应用盐酸氨溴索对观察组患者进行治疗,对两组患者的治疗效果进行分析和比较。结果对照组中11例显效,12例有效,12例无效,总有效率为65.7%;观察组中19例显效,14例有效,2例无效,总有效率为94.2%。观察组的总有效率明显高于对照组,两组患者相比差异有统计学意义(χ~2=8.438,P<0.05)。对照组的咳嗽消失时间为(2.21±0.67)d,肺部啰音消失时间为(5.32±2.24)d,体温恢复正常时间为(7.72±2.09)d,住院时间为(22.37±3.51)d,观察组的咳嗽消失时间为(1.38±0.68)d,肺部啰音消失时间为(3.07±2.11)d,体温恢复正常时间为(3.37±2.14)d,住院时间为(15.43±2.18)d。观察组的各项临床指标均明显优于对照组,两组患者相比差异有统计学意义(t=3.743、3.962、4.311、4.870,P<0.05)。结论在老年慢阻肺合并肺部感染的临床治疗中应用盐酸氨溴索具有很好的效果,可以有效改善患者的临床症状,并且减少患者的住院时间。

Objective To analyze and study the effect of ambroxol hydrochloride in the treatment of elderly patients with chronic obstructive pulmonary disease and pulmonary infection.Methods Seventy patients with chronic obstructive pulmonary disease and pulmonary infection admitted to our hospital from July 2018 to January 2019 were enrolled.The patients were randomly divided into control group and observation group according to the coin method,35 cases in each group.The patients in the control group were treated with conventional treatment.On the basis of the control group,the patients in the observation group were treated with ambroxol hydrochloride.The therapeutic effects of the two groups were analyzed and compared.Results In the control group,11 cases were markedly effective,12 cases were effective,12 cases were ineffective,and the total effective rate was 65.7%.In the observation group,19 cases were markedly effective,14 cases were effective,and 2 cases were ineffective.The total effective rate was 94.2%.The total effective rate of the observation group was significantly higher than that of the control group.Between the two groups the difference was statistically significant(χ^2=8.438,P<0.05).The disappearance time of cough in the control group was(2.21±0.67)d,the time of disappearance of lung sound was(5.32±2.24)d,the normal temperature of body temperature was(7.72±2.09)d,and the hospital stay was(22.37±3.51)d.The disappearance time of cough in the observation group was(1.38±0.68)d,the time of disappearance of lung voice was(3.07±2.11)d,the normal temperature of body temperature was(3.37±2.14)d,and the hospital stay was(15.43±2.18)d.The clinical indexes of the observation group were significantly better than the control group.The difference between the two groups was statistically significant(t=3.743,3.962,4.311,4.870,P<0.05).Conclusion The application of ambroxol hydrochloride in the clinical treatment of elderly patients with chronic obstructive pulmonary disease and pulmonary infection has a good effect,which can effectively improve the clinical symptoms of patients and reduce the length of hospital stay.