腹腔镜手术治疗急性阑尾炎的并发症及术后炎症反应分析

Analysis of Complications and Postoperative Inflammatory Response of Laparoscopic Surgery for Acute Appendicitis

目的针对急性阑尾炎的患者采用腹腔镜手术治疗的效果和对其术后炎症反应的影响。方法将2018年4-12月作为研究时段,选取上述研究时段内普外科收治的急性阑尾炎患者76例展开实验,按照不同手术方案进行平均分组,对照组38例实施传统开腹手术治疗,而研究组38例则采用腹腔镜手术治疗,将术中术后指标、术后并发症发生率以及不同时段的炎症反应指标作为评价治疗效果的判断标准。结果研究组术后并发症发生率为5.26%,显著低于对照组23.68%(χ^2=5.208,P=0.022);研究组除治疗花费高于对照组外,其余各项指标均优于对照组;术前两组血清PCT、CRP水平差异无统计学意义(P>0.05)。术后5 d研究组血清PCT(6.42±1.03)ng/mL、CRP(11.45±2.13)mg/mL水平明显优于对照组,差异有统计学意义(t=25.482、25.567,P<0.05)。结论针对急性阑尾炎的患者,推荐直接实施腹腔镜手术,可显著提升治疗效果,而且术后并发症较少、炎症反应较轻,利于机体在短时间内康复。

Objective To evaluate the effect of laparoscopic surgery on inflammatory response in patients with acute appendicitis.Methods From April to December 2018,as the study period,76 patients with acute appendicitis admitted to the above-mentioned study period were selected and divided into groups according to different surgical procedures.38 patients in the control group underwent traditional open surgery treatment,while the study group of 38 patients were treated with laparoscopic surgery,the intraoperative index,postoperative complication rate and inflammatory response indicators at different time periods as the criteria for evaluating the therapeutic effect.Results The postoperative com-plication rate of the study group was 5.26%significantly lower than that of the control group23.68%(χ^2=5.208,P=0.022).In addition to the treatment cost of the study group,the other indicators were superior to the control group.There was no statistically significant difference in serum PCT and CRP levels between the first two groups(P>0.05).The serum levels of PCT(6.42±1.03)ng/mL and CRP(11.45±2.13)mg/mL in the postoperative study group were signifi-cantly better than those in the control group,the difference was statistically significant(t=25.482,25.567,P<0.05).Conclusion For patients with acute appendicitis,it is recommended to directly perform laparoscopic surgery,which can significantly improve the treatment effect,and less postoperative complications and less inflammatory reaction,which is conducive to the recovery of the body in a short time.