宫腔因素致不孕不育应用宫腔镜治疗对生殖的影响研究

Study on the Effect of Hysteroscopic Treatment on Reproduction in Infertility Caused by Intrauterine Factors

目的分析因宫腔因素导致不孕不育患者采取宫腔镜手术治疗对于患者生殖情况的影响。方法选取2015年7月-2018年1月期间该院收治的由于宫腔因素导致不孕不育患者35例,所有患者均采取宫腔镜治疗,分析治疗结果及妊娠情况。结果治疗前宫腔黏连、子宫肌瘤发生率分别为42.8%、25.7%,治疗后分别为22.8%、5.7%,治疗前后差异无统计学意义(χ^2=10.051、10.032,P=0.000、0.000)。治疗前子宫内膜炎、子宫内膜息肉发生率分别为22.8%、8.6%,治疗后分别为17.1%、2.8%,治疗前后差异无统计学意义(χ^2=0.393、0.451,P=0.065、0.052)。35患者治疗后成功妊娠25例,妊娠率为73.5%,1例术后生殖道感染,感染率为2.8%。结论采取宫腔镜治疗由于宫腔因素导致不孕不育获得理想效果,可明显提高患者术后妊娠率,值得推荐使用。

Objective To analyze the effect of hysteroscopic surgery on the reproductive status of patients with infertili-ty caused by intrauterine factors.Methods A total of 35 patients with infertility due to uterine factors were enrolled in the hospital from July 2015 to January 2018.All patients underwent hysteroscopic treatment to analyze the treatment results and pregnancy status.Results The incidence of intrauterine adhesion and uterine fibroids before treatment was 42.8%and 25.7%,respectively.After treatment,they were 22.8%and 5.7%respectively.The difference was significant before and after treatment(χ^2=10.051,10.032,P=0.000,0.000).The incidence of endometritis and endometrial polyps before treatment was 22.8%and 8.6%,respectively,17.1%and 2.8%after treatment,and the difference was not statis-tically significant before and after treatment(χ^2=0.393,0.451,P=0.065,0.052).35 patients were successfully treated with 25 cases of pregnancy,the pregnancy rate was 73.5%,and 1 case of postoperative genital tract infection,the infection rate was 2.8%.Conclusion Hysteroscopic treatment can achieve the ideal effect of infertility due to uterine factors,which can significantly improve the postoperative pregnancy rate and is recommended.