颈部动脉粥样硬化与β-淀粉样蛋白1-42、磷脂酶A2的相关性研究及优质护理措施

Correlation between Cervical Atherosclerosis and β-amyloid 1-42, Phospholipase A2 and Quality Nursing Measures

目的探讨颈部动脉粥样硬化与β-淀粉样蛋白1-42、磷脂酶A2的相关性,总结颈部动脉粥样硬化的优质护理措施。方法回顾性分析该院自2015年5月-2017年12月符合入选标准的颈部动脉粥样硬化患者128例及健康体检的正常人100名的Aβ1-42、磷脂酶A2检查结果输入数据库,统计对比临床数据的差异性。并对颈动脉粥样硬化患者实行优质护理服务,评价患者的满意度。结果Aβ1-42在动脉粥样硬化患者中的表达(164.87±24.13)pg/mL较正常人(99.94±9.12)pg/mL增加,差异有统计学意义(P<0.05),但与动脉粥样硬化程度无关(P>0.05)。Lp-PLA2在动脉粥样硬化患者中的表达(218.07±34.93)ng/mL较正常人(102.70±26.67)ng/mL增加,差异有统计学意义(P<0.05),且随着动脉粥样硬化程度的加重(轻度(186.15±12.86)ng/mL,中度(231.37±15.08)ng/mL,重度(282.40±14.33)ng/mL而表达增加(P<0.05)。颈动脉粥样硬化患者实行优质护理服务后,满意度达97.66%。结论Aβ1-42与动脉粥样硬化相关,但不随着动脉粥样硬化程度加重而表达增加。Lp-PLA2与动脉粥样硬化相关,且随着动脉粥样硬化程度的加重而表达增加。优质护理服务可提升动脉粥样硬化患者的满意度,促进护患和谐发展。

Objective To investigate the correlation between cervical atherosclerosis andβ-amyloid 1-42,phospholi-pase A2,and to summarize the quality nursing measures for cervical atherosclerosis.Methods A retrospective analysis of the results of Aβ1-42 and phospholipase A2 in 128 patients with cervical atherosclerosis and 100 healthy subjects in the hospital from May 2015 to December 2017,the statistical comparison of clinical data.Quality care services were performed on patients with carotid atherosclerosis to evaluate patient satisfaction.Results The expression of Aβ1-42 in atherosclerosis patients(164.87±24.13)pg/mL was higher than that in normal subjects(99.94±9.12)pg/mL,the difference was statistically significant(P<0.05),but not related to the degree of atherosclerosis(P>0.05).The expression of Lp-PLA2 in atherosclerosis patients(218.07±34.93)ng/mL was higher than that in normal subjects(102.70±26.67)ng/mL,the difference was statistically significant(P<0.05),and the degree of atherosclerosis was aggravated[light degree was(186.15±12.86)ng/mL,moderate(231.37±15.08)ng/mL,severe(282.40±14.33)ng/mL and the expression increased(P<0.05).After the implementation of quality nursing services for patients with carotid atherosclerosis,the satisfaction rate reached 97.66%.Conclusion Aβ1-42 is associated with atherosclerosis,but it does not increase with the severity of atherosclerosis.Lp-PLA2 is associated with atherosclerosis and increases in expression as the degree of atherosclerosis increases.Quality care services can improve the satisfaction of patients with atherosclerosis and promote the harmo-nious development of nurses and patients.