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膳食黄酮消脂减肥的分子作用机制研究进展 被引量:6

Molecular Mechanisms of the Fat-lowering and Weight-losing Properties of Dietary Flavonoids: A Review
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摘要 肥胖已经成为全球最严重的公共健康问题之一。除了对形体和心理带来的负面影响外,它还能引起心血管疾病、2型糖尿病和高血压等众多慢性疾病。大量的科学研究和流行病学调查表明,黄酮类化合物作为一大类普遍存在于人类膳食中的植物次生代谢产物,具有现实的消脂减肥作用,逐渐受到越来越多的关注。本文结合国内外最新研究进展,综述了肥胖的特点及其与慢性炎症的关系,黄酮的结构及来源,黄酮体内代谢和消脂减肥的分子机制,并在此基础上提出以膳食黄酮为主要功能成分的消脂减肥类产品的研发建议,以期为日益庞大的肥胖及超重群体提供精准膳食干预的食疗思路。 Obesity is one of the most serious global health problems.Regardless of obesity has an adverse impact on human somatotype and mentality,it can increase the risk of other different chronic diseases,such as cardiovascular disease,diabetes mellitus type II and hypertension.A growing number of scientific studies and epidemiological surveys show that flavonoids are a large class of nature polyphenols without side effect and have the actual activity of fat-lowering and weight-losing.In this paper,based on the latest research,related obesity characteristics,relationship of obesity and chronic inflammation,structure and source of flavonoids,metabolism kinetics and molecular mechanisms of the anti-obesity had been discussed.The research and development suggestion of weight-losing products main containing dietary flavonoids was also put forward,in order to offer a diet of precise dietary interventions for an increasingly large number of overweight and obese groups.
作者 陈玉峰 付诗尧 金露 李云虹 张英 Chen Yufeng;Fu Shiyao;Jin Lu;Li Yunhong;Zhang Ying(College of Biosystems Engineering and Food Science,Fuli Institute of Food Science,Zhejiang Key Laboratory for Agro-Food Processing,Zhejiang R&D Center for Food Technology and Equipment,Zhejiang University,Hangzhou 310058)
出处 《中国食品学报》 EI CAS CSCD 北大核心 2019年第10期315-330,共16页 Journal of Chinese Institute Of Food Science and Technology
基金 广东省重点研发计划项目
关键词 植物黄酮 膳食干预 消脂 减肥 分子机制 plant flavonoids dietary intervention fat-lowering weight-losing molecular mechanisms
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