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扩张性心肌病患儿血清脑钠肽、尿酸及降钙素原水平变化研究 被引量:2

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摘要 目的探讨血清脑钠肽(BNP)、降钙素原(PCT)及尿酸(UA)在扩张性心肌病(DCM)患儿病情评估中的应用价值。方法将2016年1月-2017年6月郑州瑞祥医院儿科收治的78例DCM患儿,为观察组,根据NYHA分级为:Ⅱ级(22例)、Ⅲ级(30例)、Ⅳ级(26例);并根据UA表达水平分为正常UA组26例和高UA组52例;并选择同期健康体检者60例为对照组。所有受试对象均检测各组血清BNP、UA和PCT表达水平。结果78例DCM患儿高UA组、正常UA组血清BNP、UA和PCT表达均明显高于对照组(均P<0.05);DCM患儿不同NYHA分级血清BNP、UA和PCT表达均明显高于对照组(均P<0.05);不同NYHA分级随病情严重程度,三指标均呈递增趋势,且均为正相关性趋势(均P<0.05)。结论血清BNP、UA和PCT可作为扩张性心肌病患儿病情评估、疾病监测及预后判断的灵敏指标,血清BNP、UA和PCT联合应用可为临床医师提供可靠的实验室指标支持。
作者 张娟
出处 《临床研究》 2019年第11期145-146,共2页 Clinical Research
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