玻璃体腔注射康柏西普和视网膜光凝联合治疗视网膜中央静脉阻塞黄斑水肿的疗效观察

Therapertic efect of intravitreal injection of Conbercep and retinalphotocoagulation in the treatment of macular edema with central retinal vein occlusion

目的探究玻璃体腔注射康柏西普和视网膜光凝联合治疗视网膜中央静脉阻塞黄斑水肿的疗效。方法回顾性分析,将2014年1月~2017年1月在我院接受治疗的60例(60眼)视网膜中央静脉阻塞黄斑水肿患者作为研究对象,并给予随机分组,对照组30例(30眼),给予单纯视网膜光凝治疗;干预组30例(30眼),在对照组基础上加用康柏西普玻璃体腔注射治疗,对两组患者治疗前后的最佳矫正视力(BCVA)、黄斑中心视网膜厚度(CMT)以及眼内压(IOP)进行综合评价。结果干预组患者治疗后的BCVA指标显著优于对照组(P<0.05),有统计学意义;干预组治疗后的CMT明显降低,与对照组差异存在统计学意义(P<0.05);且两组治疗后的IOP指标与治疗前差异无统计学意义,组间比较差异无统计学意义(P>0.05)。结论采用玻璃体腔注射康柏西普联合视网膜光凝治疗视网膜中央静脉阻塞黄斑水肿,能够缓解黄斑水肿,提升患者视力,疗效显著,值得推广应用。

Objetive To investigate the efficacy of intravitreal injection of Conbercep and retinalphotocoagulation in the treatment of macular edema with central retinal vein occlusion.Methods A retrospective analysis was performed on 60 patients(60 eyes)with central retinal vein occlusion and macular edema who were treated in our hospital from January 2014 to January 2017.The patients were randomized grouped.30 patients(30 eyes)in the control group give were treatment with retina photocoagulation alone,while 30 patients(30 eyes)in the intervention group were treated with retina photocoagulation combining with Conbercep intravitreal injection.The best corrected visual acuity(BCVA)before and after treatment in the two groups of patients,The macular central retinalthickness(CMT)and intraocular pressure(IOP)were comprehensively evaluated.Results The BCVA index of the intervention group was significantly better than that of the control group(P<0.05)The CMT of the intervention group was significantly lower than that of the control group(P<0.05).There was no significant difference in the IOP between the two groups after treatment.Conclusion Intravitreal injection of Conbercep combined with retina photocoagulation for macular edema in central retinal vein occlusion can relieve macular edema and improve visual acuity.The curative effect is significant and worthy of popularization and application.