慢性乙型肝炎患者免疫球蛋白检验的临床意义

Clinical Significance of Immunoglobulin Test in Patients With Chronic Hepatitis B

目的研究慢性乙型肝炎患者免疫球蛋白检验的临床意义。方法研究2019年1-6月收治的慢性乙型肝炎患者150例为研究组,按照乙肝病情分成两组,其中重型肝炎75例为研究A组,轻中度肝炎75例为研究B组;选取同时期健康体检健康人员120例为对照组;所有研究对象抽取外周静脉血检验免疫球蛋白,比较三组指标。结果研究A组、研究B组免疫球蛋白IgM、IgG、IgA指标均高于对照组,比较差异有统计学意义,P<0.05。研究A组患者免疫球蛋白指标高于研究B组,比较差异有统计学意义,P<0.05。结论慢性乙型肝炎患者免疫球蛋白检验对患者慢性乙型肝炎诊断,严重程度及治疗效果均有提示作用。

Objective To study the clinical significance of immunoglobulin test in patients with chronic hepatitis B.Methods During the study period from January to June 2019,150 patients with chronic hepatitis B were divided into two groups according to the condition of hepatitis B.Among them,75 cases of severe hepatitis were studied in group A,and mild to moderate hepatitis was studied in group B.120 healthy controls were selected from healthy subjects at the same time;all subjects were selected for peripheral venous blood test for immunoglobulin,and three groups of indicators were compared.Results The immunoglobulins IgM、IgG、IgA in group A and group B were significantly higher than those in the control group,and the difference was statistically significant(P<0.05).The immunoglobulin index of group A patients was higher than that of study group B,and the difference was statistically significant(P<0.05).Conclusion Immunoglobulin test in patients with chronic hepatitis B has a suggestive effect on the diagnosis,severity and treatment of chronic hepatitis B.