复方生精汤治疗少弱精子症男性不育临床研究

Clinical Study of Fufang Shengjing Decoction in Treatment of Male Infertility with Asthenospermia

目的:探讨复方生精汤治疗少弱精子症男性不育的临床疗效。方法:选择2014年1月至2017年12月收治的男性不育症患者60例,随机分为观察组与对照组各30例。观察组采用复方生精汤治疗,对照组采用六味地黄丸治疗。比较两组患者临床疗效、精子存活率、精子密度、精子活力、性激素水平。结果:观察组治愈及总有效人数多于对照组,差异有统计学意义(P<0.05);治疗后两组精子密度、精子存活率、a级活力以及a级+b级活力均显著高于治疗前,差异有统计学意义(P<0.05),且观察组精子存活率、a级活力以及a级+b级活力显著高于对照组,差异有统计学意义(P<0.05);治疗后两组患者性激素指标较治疗前均有改善(P<0.05),但组间比较差异无统计学意义(P> 0.05)。结论:复方生精汤可通过提高精子质量、改善激素水平治疗少弱精子症男性不育。

Objective:To explore the clinical efficacy of Fufang Shengjing Decoction in the treatment of male infertility with asthenospermia. Methods:A total of 60 male patients with infertility with asthenospermia admitted from January 2014 to December 2017 were selected and randomly divided into the observation group and the control group,with 30 patients in each group. The control group was treated with Liuwei Dihuang Pills while the observation group was treated with Fufang Shengjing Decoction. Clinical effect,sperm survival rate,sperm density,sperm vitality and sex hormone level of the two groups were compared. Results:The cure rate and total effective rate of the observation group were significantly higher than those of the control group,the difference was statistically significant(P< 0.05). Sperm density,sperm survival rate,the class a vitality and the class a + b vitality after treatment in the two groups were better than those before treatment,the difference was statistically significant(P< 0.05). Sperm survival rate,the class a vitality and the class a + b vitality after treatment in the observation group were better than those in the control group,the difference was statistically significant(P< 0.05). After treatment,the sex hormone levels of the two groups were improved(P< 0.05),but there was no statistical difference between the two groups(P> 0.05). Conclusions:Fufang Shengjing Decoction can significantly improve the sperm quality and improve the hormone level in the treatment of male infertility with asthenospermia.