脑苷肌肽治疗小儿病毒性脑炎的临床研究

Clinical Study on Cattle Encephalon Glycoside and Ignotin in Treatment of Children with Viral Encephalitis

目的:探讨脑苷肌肽治疗小儿病毒性脑炎的临床效果。方法:选择2018年1~12月我院收治的病毒性脑炎患儿112例为研究对象,按随机数表法分为研究组(n=56)与对照组(n=56)。对照组采用阿昔洛韦抗病毒、降温、降低颅内压等常规治疗,研究组在常规治疗基础上采用脑苷肌肽治疗,对比两组治疗效果、临床症状、体征改善时间以及不良反应发生情况。结果:与对照组相比,研究组治疗总有效率更高,头痛消失、呕吐消失、体温恢复正常及意识清醒时间较对照组均差异具有统计学意义(P<0.05);两组均未出现不良反应,差异无统计学意义(P>0.05)。结论:脑苷肌肽治疗小儿病毒性脑炎安全高效,可快速地改善患儿临床症状与体征,可为临床应用提供参考。

Objective:To investigate the clinical effects of cattle encephalon glycoside and ignotin in treatment of children with viral encephalitis.Methods:112 children with viral encephalitis who admitted in the hospital from January to December 2018 were selected as the subjects.All patients were divided into research group(n=56)and control group(n=56)by random number table.Control group was given routine treatment,and research group was treated with cattle encephalon glycoside and ignotin based on routine treatment.The curative effects,clinical symptoms,improvement time of signs,adverse reactions were compared between the two groups.Results:Compared with control group,the total effective rate of research group was higher,while the disappearance time of headache and vomiting,recovery time of temperature,awakening time of consciousness in research group were shorter(P<0.05);There were no adverse reactions in the two groups,and the difference was not statistically significant(P>0.05).Conclusion:Cattle encephalon glycoside and ignotin in treatment of children with viral encephalitis is safe and effective,it can improve clinical symptoms and signs,which has higher clinical application value.