辛温复辛凉法辅助治疗小儿流行性感冒的临床疗效探讨

Clinical Effect of Xinwen Fuxinliang Method on Adjuvant Treatment of Pediatric Influenza

目的分析帕拉米韦联合中药治疗流行性感冒的临床疗效。方法选取该科2018年1月—2019年3月收治68例流行性感冒的患儿作为研究对象,随机分为两组:对照组应用帕拉米韦进行治疗;观察组应用帕拉米韦联合中药进行治疗,疗程3 d。疗程结束后与对照组比较有效率,症状改善时间及症候积分。结果观察组的治疗有效率为97.06%,明显高于对照组的91.17%,差异有统计学意义(χ^2=10.118,P<0.05);观察组治疗后发热改善时间(43.35±5.13)h,明显短于对照组发热改善时间(59.14±7.01)h,观察组流感症状改善时间(43.28±4.98)h,短于治疗组流感症状改善时间(58.11±6.52)h,差异有统计学意义(t=9.874、7.093;P<0.05)。治疗72 h症候积分观察组(6.76±2.12)分,治疗组(9.98±2.11)分,改善明显优于对照组,差异有统计学意义(t=10.092,P<0.05)。结论应用帕拉米韦联合中药治疗流行性感冒能够缩短流感症状时间,提高临床疗效,值得推广。

Objective To analyze the clinical efficacy of peramivir combined with traditional Chinese medicine in the treatment of influenza.Methods A total of 68 children with influenza were enrolled in our department from January 2018 to March 2019.They were randomly divided into two groups:the control group was treated with peramivir;the observation group was treated with peramivir.Combined with traditional Chinese medicine for treatment,the course of treatment is 3 days.After the end of the treatment,it was more effective than the control group,symptom improvement time and symptom score.Results The effective rate of the observation group was 97.06%,which was significantly higher than that of the control group(91.17%).The difference was statistically significant(χ^2=10.118,P<0.05).The improvement time of fever in the observation group was(43.35±5.13)h,which was significantly shorter than that of the observation group.The improvement time of fever in the control group was(59.14±7.01)h,and the improvement time of influenza symptoms in the observation group was(43.28±4.98)h,which was shorter than that in the treatment group(58.11±6.52)h.The difference was statistically significant(t=9.874,7.093;P<0.05).The 72-hour symptom score observation group was(6.76±2.12)points,and the treatment group was(9.98±2.11)points.The improvement was significantly better than the control group,and the difference was statistically significant(t=10.092,P<0.05).Conclusion The use of peramivir in combination with traditional Chinese medicine to treat influenza can shorten the time of flu symptoms and improve clinical efficacy,which is worth promoting.