调神通督针刺法治疗血管性痴呆的Meta分析

Meta-analysis of Tiaoshen Tongdu Acupuncture in the Treatment of Vascular Dementia

目的:综合评价近年来调神通督针刺法治疗血管性痴呆的临床疗效。方法:以调神通督针法治疗血管性痴呆为检索词,检索中国知网、万方数据库、维普近10年来在国内公开发表的调神通督针刺法治疗血管性痴呆的临床随机对照研究,对纳入的文献进行异质性分析及固定效应模型分析或描述性系统评价,并对其发表偏倚分析。结果:共纳入6项研究,434例血管性痴呆患者,Meta分析显示:调神通督针刺法治疗血管性痴呆的总有效率优于对照组(P<0.01),漏斗图不对称,提示可能存在偏倚。结论:本研究提示调神通督针刺法治疗血管性痴呆有明确的疗效,但由于样本量过小,且纳入文献整体质量不高,使结果可能存在偏差,尚需更大样本、更高质量数据的支持。

Objective:Comprehensive evaluation of the clinical efficacy of Tiaoshen Tongdu acupuncture in the treatment of vascular dementia in recent years.Methods:Using Tiaoshen Tongdu acupuncture in the treatment of Vascular Dementia as a search term,we searched the clinical randomized controlled studies published in CNKI,Wanfang database and VIP in recent 10 years.Heterogeneity analysis and fixed-effect model analysis or descriptive systematic evaluation of the included literature were conducted,and publication bias was analyzed.Results:A total of 6 studies,434 patients with vascular dementia,meta-analysis showed that:The total effective rate of Tiaoshen Tongdu acupuncture in the treatment of vascular dementia was better than that of the control group(P<0.01).The funnel diagram was asymmetric,suggesting that there might be bias.Conclusion:This study suggests that Tiaoshen Tongdu acupuncture has definite curative effect on vascular dementia,but the results may be biased due to the small sample size and the low quality of the literature,which needs the support of larger samples and higher quality data.