葛根素注射液结合硫酸镁治疗妊娠高血压综合征临床疗观察

Clinical Observation of Puerarin Injection Combined with Magnesium Sulfate in the Treatment of Pregnancy Induced Hypertension

目的:观察分析葛根素注射液联合硫酸镁治疗妊娠高血压综合征的疗效。方法:选取符合标准的60例妊娠高血压综合征患者分组研究,以数字随机表法将其分成治疗组(n=30)与对照组(n=30),2组入院后均行常规治疗,包括镇静、低流量吸氧等,对照组在此基础上给予硫酸镁注射液治疗,治疗组在对照组基础上结合葛根素注射液治疗,对2组治疗后患者血压水平变化、临床疗效、妊娠结局、不良反应进行比较分析。结果:2组治疗前血压水平相比,差异不显著(P>0.05),治疗组治疗后SBP、DBP、MAP水平与对照组相比,均相对更低(P<0.05);治疗组总有效率为93.33%,与对照组73.33%相比,相对更高(P<0.05);治疗组自然分娩率与对照组相比,相对更高,产后出血率、新生儿窒息率、胎儿宫内窘迫率与对照组相比,相对更低(P<0.05);治疗组不良反应率为6.67%,与对照组23.33相比,相对更低(P<0.05)。结论:应用葛根素注射液联合硫酸镁治疗妊娠高血压综合征可降低患者血压水平,改善妊娠结局,不良反应较少。

Objective:To observe the effect of Puerarin injection combined with magnesium sulfate in the treatment of pregnancy-induced hypertension syndrome.Methods:60 patients with pregnancy-induced hypertension syndrome who met the criteria were selected and divided into treatment group(n=30)and control group(n=30)by digital random table method.Both groups received routine treatment after admission.Including sedation,low-flow oxygen inhalation,the control group was given magnesium sulphate injection on the basis of this,the treatment group was treated with Puerarin injection on the basis of the control group,the blood pressure level changes,clinical efficacy,pregnancy of the two groups after treatment The outcome and adverse reactions were compared and analyzed.Results:There was no significant difference in blood pressure levels between the two groups before treatment(P>0.05).The levels of SBP,DBP and MAP in the treatment group were lower than those in the control group(P<0.05).The efficiency was 93.33%,which was relatively higher than that of the control group(73.33%)(P<0.05).The natural delivery rate of the treatment group was relatively higher than that of the control group.Postpartum hemorrhage rate,neonatal asphyxia rate,intrauterine distress The rate was relatively lower than that of the control group(P<0.05);the adverse reaction rate in the treatment group was 6.67%,which was relatively lower than that in the control group(23.33)(P<0.05).Conclusion:The application of Puerarin injection combined with magnesium sulfate in the treatment of pregnancy-induced hypertension syndrome can reduce blood pressure levels,improve pregnancy outcomes,and have fewer adverse reactions.