不同剂量右美托咪定在妇科腹腔镜中的应用

Application of Different Doses of Dexmedetomidine in Gynecological Laparoscopy

目的对妇科腹腔镜手术患者使用不同剂量右美托咪定后患者的清醒状态展开全面分析。方法本院在2017年3月-2018年3月收治50例采取腹腔镜手术的妇科患者,所有患者均给予右美托咪定,利用电脑软件随机分组,25例划入对照组(低剂量0.5μg/kg)剩余25例收入研究组(高剂量1.0μg/kg),对比两种剂量下患者的意识恢复时间以及苏醒时间,同时对比两组躁动评分。结果研究组躁动评分低于对照组,研究组(意识恢复时间、苏醒时间)短于对照组;研究组在麻醉后MMSE以及TMT评分高于对照组,P <0.05。结论对妇科腹腔镜手术患者使用大剂量右美托咪定后能够有效改善术前躁动状态,缩短术后意识恢复时间。

Objective To analyze the awake state of patients undergoing gynecological laparoscopic surgery with different doses of dexmedetomidine. Methods From March 2017 to March 2018, 50 gynecologic patients underwent laparoscopic surgery were enrolled in our hospital. All patients were given dexmedetomidine, randomized by computer software, and 25 patients were assigned to the control group(low dose: 0.5 μg/kg) The remaining 25 patients in the study group(high dose: 1.0 μg/kg) compared the patients’ consciousness recovery time and recovery time at the two doses, and compared the two groups’ agitation scores. Results The agitation score of the study group was lower than that of the control group. The study group(conscious recovery time and recovery time) was shorter than the control group. The MMSE and TMT scores of the study group were higher than those of the control group after anesthesia, P < 0.05. Conclusions for gynecologic laparoscopic surgery patients The use of high-dose dexmedetomidine can effectively improve the preoperative restlessness and reduce postoperative recovery time.