非酒精性脂肪性肝病相关肝细胞癌的研究进展

Research Progress on Hepatocellular Carcinoma Associated with Nonalcoholic Fatty Liver Disease

目前,受到我国肥胖人群比例不断上升、糖尿病患者数量不断增加等多方面因素的影响,非酒精性脂肪性肝病患者的数量较之以往也出现了明显增多。对于非酒精性脂肪性肝病患者而言,其发病与肝细胞癌之间存在极为密切的联系,且非酒精性脂肪性肝病未来将会成为引发肝细胞癌的主要诱因之一。在临床相关研究当中,非酒精性脂肪性肝病相关性肝细胞癌患者的病情带有较强的隐匿性,很多患者长期无明显症状,这就导致很多患者对病情存在忽略,在临床确诊的时候病情一般已经发展至中晚期,患者的整体预后情况很差。在此背景下,针对非酒精性脂肪性肝病相关肝细胞癌患者进行多方面研究十分必要,对于这类患者的临床治疗存在重要意义。

At present,due to the increasing proportion of obese people in China and the increasing number of diabetic patients,the number of patients with nonalcoholic fatty liver disease has increased significantly compared with the past.For patients with nonalcoholic fatty liver disease,there is a close relationship between the onset and hepatocellular carcinoma,and non-alcoholic fatty liver disease will become one of the main causes of hepatocellular carcinoma in the future.In clinically relevant studies,patients with nonalcoholic fatty liver disease-associated hepatocellular carcinoma have a strong occultity,and many patients have no obvious symptoms for a long time,which leads to many patients neglecting the condition,at the time of clinical diagnosis.The condition has generally progressed to the middle and late stages,and the overall prognosis of the patient is very poor.In this context,it is necessary to conduct multi-faceted research on patients with non-alcoholic fatty liver disease-related hepatocellular carcinoma,and it is of great significance for the clinical treatment of such patients.