儿童肠易激综合征研究进展

Progress in studying irritable bowel syndrome in children

肠易激综合征(IBS)是一种常见的功能性胃肠病,是儿童腹痛的常见病因。其发病机制尚未完全明确,目前认为与消化道动力异常、内脏高敏感、脑-肠轴功能紊乱等因素有关。儿童IBS常表现为腹痛、腹胀、伴排便习惯改变,临床表现缺乏特异性,诊断参考罗马Ⅳ标准。对IBS患儿而言,治疗的最终目的是提高生活质量,包括减轻疼痛、使排便频率及粪便性状恢复正常,治疗方式主要包括调整饮食及生活方式、药物治疗等。现就近年来关于儿童IBS的发病机制、诊断、治疗等方面作一综述。

Irritable bowel syndrome(IBS)is a common functional gastrointestinal disorder,and is also a common cause of recurrent abdominal pain in children.The pathogenesis of IBS has not been completely clarified,and it is currently believed to be related to factors such as gastrointestinal dysmotility,visceral hypersensitivity,and brain-gut axis dysfunction.Pediatric IBS often shows abdominal pain,bloating,accompanied by altered bowel habits,while its clinical manifestations are not specific.The diagnosis of IBS is usually made based on the RomeⅣcriteria.The ultimate goal of treatment is to improve the quality of life of children,including alleviating the abdominal pain of children and restoring normal bowel habits.The treatment mainly includes adjusting diet and lifestyle,medicine etc.This review is to investigate the progress of the pathogenesis,diagnosis and treatment of IBS in recent years.