沟槽状胰腺炎诊断治疗最新进展

Recent advances in diagnosis and treatment of grooved pancreatitis

沟槽状胰腺炎(GP)是一种罕见的慢性胰腺炎,其病变累及由胰头背部、十二指肠降部、胆总管远端、壶腹、后腹膜构成的解剖区域——“沟槽状区域”。由于其发病部位特殊、病因尚不明确、临床表现缺乏特异性,并与其他实体病变有相似的影像学和组织病理学特征,因此其诊断具有一定的挑战性。随着影像学技术的发展,GP逐渐被熟知。文章对该病的发病机制、诊断及治疗的最新进展进行综述,以加强认识,提高确诊率和治愈率。

Grooved pancreatitis(GP)is a rare chronic pancreatitis.Its pathological changes involve the grooved area,which consists of the back of the head of the pancreas,the descending duodenum,the distal end of the common bile duct,the ampulla and the posterior peritoneum.Because of its special location,unclear etiology,lack of specificity in clinical manifestations,and similar imaging and histopathological features with other solid lesions,its diagnosis is challenging.With the development of imaging technology,GP is gradually known.This article reviews the latest progress in the pathogenesis,diagnosis and treatment of the disease in order to enhance understanding and improve the diagnosis and cure rate.