摘要
Objective:To investigate the clinical efficacy of plasma exchange therapy for autoimmune bullous skin disease.Methods:Fifty patients with autoimmune bullous skin disease enrolled in our hospital from January 2018 to January 2019 were selected.The patients were grouped by treatment method:25 control group patients were given conventional hormone therapy,while 25 experimental group patients were treated with plasma exchange therapy;efficacy of treatment was compared between two groups of patients.Results:Initial dose,maximum dose,and cumulative dose of glucocorticoids were lower in experimental group patients than those in control group(P<0.05).Incidence of complication was lower in experimental group patients than those in control group(P<0.05);the difference was significant.There was no significant difference in short-term efficacy between the two groups(P>0.05).Conclusion:The application of plasma exchange therapy was effective for treatment of autoimmune bullous skin disease.It could reduce dosage amount of glucocorticoids and incidence of complications;its application can be promoted.
