摘要
目的:分析为患儿输注抗菌药物后其发生药物不良反应(ADR)的规律和特点。方法:对2011年4月至2019年1月期间在海口市妇幼保健院输注抗菌药物后发生不良反应的210例患儿的临床资料进行回顾性研究。分析其ADR报告,统计其性别、年龄、所用抗菌药物的类型、ADR的主要受累器官/系统及临床表现、治疗转归情况等。结果与结论:这210例患儿的男女比例为1.57:1;其中年龄为17d^3岁患儿ADR的发生率为69.52%;其中因使用头孢菌素类抗菌药物而发生ADR患儿的占比为51.13%;其中ADR主要累及器官/系统为皮肤及皮肤附件患儿的占比为88.03%。
objective:to analyze the rule and characteristics of adverse drug reaction(ADR)after infusing antibiotics into children.Methods:a retrospective study was conducted on the clinical data of 210 children with adverse reactions after infusion of antibiotics in haikou maternal and child health hospital from April 2011 to January 2019.Analyze their ADR reports and make statistics of their gender,age,type of antibacterial drugs used,main organs/systems affected by ADR,clinical manifestations,treatment outcomes,etc.Results and conclusion:the male-female ratio of 210 children was 1.57:1.The incidence of ADR in children aged 17 days to 3 years was 69.52%.The proportion of children with ADR caused by cephalosporins was 51.13%.Among them,88.03% of children with ADR mainly involved organs/systems of skin and skin appendages.
作者
王彬
赵汝霞
吴眉
Wang bin;zhao ruxia;wu mei(haikou maternal and child health care center,haikou Hainan 570203)
关键词
抗菌药物
儿童
不良反应
antibacterial drugs
Children
Adverse reactions
