肝脏CT灌注成像在肝癌早期诊断中的临床应用探讨

Clinical Study for the Liver CT Perfusion Imaging in Early Diagnosis of Liver Cancer

目的:探讨肝脏CT灌注成像在肝癌早期诊断中的应用价值。方法:以2015年2月至2018年3月临床确诊的70例肝癌患者为例,均实施CT灌注成像检查,分析对比检查结果。结果:肝硬化实质HAF(0.22±0.04)、BF(148.35±38.45)mL/(min/100g)、BV(15.21±5.03)mL/(min/100g),与肝癌小病灶值相比均明显较低(P<0.05);BV临界值=28.162时,ROC曲线特异度=100.00%,灵敏度=79.31%,HAF临界值=0.3027时,ROC曲线特异度=90.00%,灵敏度=100.00%,BF临界值=410.362时,ROC曲线特异度=60.00%,灵敏度=86.11%。结论:肝脏CT灌注成像在肝癌诊断中的应用价值显著,可以作为疾病早期诊断和治疗方案选取的有效依据。

Objective: To explore the value of liver CT perfusion imaging in the early diagnosis of liver cancer. Methods: Seventy patients with liver cancer diagnosed clinically from February 2015 to March 2018 were enrolled in the study. The CT perfusion imaging was performed and the results of the comparison were analyzed. Results: The HAF(0.22±0.04),BF(148.35±38.45)mL/(min/100 g), BV(15.21±5.03)mL/(min/100 g) of liver cirrhosis was significantly higher than the small lesions of liver cancer(P <0.05).When BV critical value=28.162, ROC curve specificity=100.00%, sensitivity=79.31%, HAF critical value=0.3027, ROC curve specificity=90.00%, sensitivity=100.00%, BF critical value=410.362, ROC curve specificity=60.00%, sensitivity=86.11%. Conclusion: Liver CT perfusion imaging has a significant value in the diagnosis of liver cancer, and it could be used as an effective basis for the early diagnosis and treatment of disease.