男性腔隙性脑梗死共危险饮酒与非危险饮酒患者神经心理学及人格特点差异的对比分析

Differences of Neuropsychological and Personalistic Characteristics between Male Lacunar Infarction Patients with Hazardous Drinking and Non-hazardous Drinking:a Contrastive Analysis

目的对比分析男性腔隙性脑梗死共危险饮酒与非危险饮酒患者神经心理学及人格特点的差异。方法选取2016年5-10月华中科技大学同济医学院附属同济医院神经内科门诊及住院部收治的男性腔隙性脑梗死患者124例,根据其危险饮酒情况分为共危险饮酒组52例和非危险饮酒组72例。比较两组患者一般资料(包括年龄、文化程度、职业类型、吸烟史及父母饮酒情况)及蒙特利尔认知评估量表(MoCA)评分、艾森克人格问卷(EPQ)评分、症状自评量表(SCL-90)评分。结果(1)两组患者年龄、文化程度、职业类型比较,差异无统计学意义(P>0.05);两组患者吸烟史、父母饮酒情况比较,差异有统计学意义(P<0.05)。(2)共危险饮酒组、非危险饮酒组患者认知障碍发生率分别为59.6%、56.9%,差异无统计学意义(P>0.05)。共危险饮酒组患者视空间与执行功能、记忆、注意力评分及MoCA总分低于非危险饮酒组(P<0.05);两组患者命名、语言、抽象思维及定向力评分比较,差异无统计学意义(P>0.05)。(3)共危险饮酒组患者内外向性(E)、神经质(N)、精神质(P)评分高于非危险饮酒组(P<0.05);两组患者掩饰性(L)评分比较,差异无统计学意义(P>0.05)。(4)共危险饮酒组患者躯体化、人际关系敏感、焦虑、敌对、偏执、精神病性因子评分及SCL-90总均分高于非危险饮酒组(P<0.05);两组患者强迫症状、抑郁、恐怖因子评分比较,差异无统计学意义(P>0.05)。结论与男性腔隙性脑梗死非危险饮酒患者相比,男性腔隙性脑梗死共危险饮酒患者视空间与执行功能、记忆力及注意力损伤较重,存在明显人格改变,认知功能及心理健康状态较差,因此临床应加强对男性腔隙性脑梗死共危险饮酒患者的重视。

Objective To contrastively analyze the differences of neuropsychological and personalistic characteristics between male lacunar infarction patients with hazardous drinking and non-hazardous drinking.Methods From May to October 2016,a total of 124 male outpatients and inpatients with lacunar infarction were selected in the Department of Neurology,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,and they were divided into hazardous drinking group(n=52)and non-hazardous drinking group(n=72)according to the dangerous drinking situation.General information(including age,educational level,vocational types,smoking history and drinking situation of parents),MoCA score,EPQ score and SCL-90 score were compared between the two groups.Results(1)No statistically significant difference of age,educational level or vocational types was found between the two groups(P>0.05),while there was statistically significant difference in smoking history and drinking situation of parents between the two groups,respectively(P<0.05).(2)Incidence of cognitive disorder in hazardous drinking group and non-hazardous drinking group was 59.6%and 56.9%,respectively,showed no statistically significant difference(P>0.05).Visuospatial and executive function score,memory score,attentiveness score and total MoCA score in hazardous drinking group were statistically significantly lower than those in non-hazardous drinking group(P<0.05),while no statistically significant difference of naming score,language score,abstract thinking score or orietation score was found between the two groups(P>0.05).(3)Extroversion and introversion score,nervousness score and psychoticism score in hazardous drinking group were statistically significantly higher than those in non-hazardous drinking group(P<0.05),while no statistically significant difference of lie or feint score was found between the two groups(P>0.05).(4)Score of somatization factor,interpersonal sensitivity factor,anxiety factor,hostility factor,bigotry factor and psychosis factor,and total SCL-90 score in hazardous drinking group were statistically significantly higher than those in non-hazardous drinking group(P<0.05),while no statistically significant difference of score of obsessive-compulsive symptom factor,depression factor or terrorist factor was found between the two groups(P>0.05).Conclusion Compared with those in male lacunar infarction patients with non-hazardous drinking,male lacunar infarction patients with hazardous drinking showed worse visuospatial and executive function,memory,attentiveness,cognitive function and mental health status,with more obvious change of personality,thus we should pay more attention to the male lacunar infarction patients with hazardous drinking.