白癜风的外科治疗进展

The Development of Surgical Treatment for Vitiligo

白癜风是皮肤科常见的一种色素脱失性皮肤黏膜疾病,发病原因可能和神经内分泌、遗传、细胞毒性、氧化应激、自身免疫和生化等因素有关。白癜风治疗困难,临床上常用的治疗方法有口服或外用糖皮质激素、免疫调节剂、中医中药、光疗以及外科手术等。近年来,随着对白癜风发病机制的不断深入研究,治疗上许多新技术、新药物层出不穷,特别是随着细胞培养技术和组织工程技术的发展,外科手术移植的方法给白癜风的治疗带来了新的希望。本文就近年来白癜风的外科治疗进展综述如下。

Vitiligo is a common pigmented skin and mucous membrane disease in dermatology,for which the pathogenesis may be related to neuroendocrine,genetics,cytotoxicity,oxidative stress,autoimmune and biochemical factors.The treatment of vitiligo is difficult,and the commonly used clinical treatment methods include oral or external glucocorticoid,immunomodulator,traditional Chinese medicine,phototherapy,as well as surgery and so on.In recent years,with the continuous in-depth study of the pathogenesis of vitiligo,many new technologies and drugs have emerged.Especially with the development of cell culture technology and tissue engineering technology,surgical transplantation has brought new hope for the treatment of vitiligo.In this review,the progress of surgical treatment of vitiligo in recent years is summarized.