低分子肝素钙预防腹腔镜术后下肢静脉血栓的效果

Effect of low molecular weight heparin calcium on prevention of lower extremity venous thrombosis after laparoscopic surgery

目的探讨低分子肝素钙预防腹腔镜术后下肢静脉血栓的效果。方法采用随机数字表法将2018年4月至2019年4月于我院接受腹腔镜手术治疗的86例患者分为对照组(43例)和观察组(43例)。对照组接受腹腔镜手术治疗,观察组在对照组基础上接受低分子肝素钙抗凝治疗。比较两组的治疗效果。结果治疗后,观察组的纤维蛋白原和D-二聚体水平均低于对照组(P<0.05)。治疗前、后,两组患者的PT和APTT均无显著差异(P>0.05)。治疗后,观察组的下肢周径小于对照组,血流速度快于对照组(P<0.05)。结论低分子肝素钙应用于腹腔镜术后患者中可有效改善其血流状态,进而降低下肢静脉血栓发生率。

Objective To investigate the effect of low molecular weight heparin calcium on prevention of lower extremity venous thrombosis after laparoscopic surgery. Methods Eighty-six patients who received laparoscopic surgery in our hospital from April 2018 to April 2019 were divided into control group(43 cases) and observation group(43 cases) by random number table method. The control group received laparoscopic surgery, while the observation group received anticoagulation treatment with low molecular weight heparin calcium on the basis of the control group. The therapeutic effects of the two groups were compared. Results After treatment, the levels of fibrinogen and D-dimer in the observation group were lower than those in the control group(P<0.05). There were no significant differences in PT and APTT between the two groups before and after treatment(P>0.05). After treatment, the peripheral diameter of the lower limbs in the observation group was smaller than that in the control group, and the blood flow velocity was faster than that in the control group(P <0.05). Conclusion Low molecular weight heparin calcium applied to patients after laparoscopic surgery can effectively improve the blood flow of patients, and then reduce the incidence of lower extremity venous thrombosis.