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血清可溶性ST2对老年急性心力衰竭患者病情程度及预后的评估价值 被引量:6

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摘要 目的分析血清可溶性ST2(sST2)对老年急性心力衰竭患者病情程度及预后的评估价值。方法回顾性分析鞍山市中心医院2016年3月~2018年2月收治的100例老年急性心力衰竭患者临床资料,按心功能分级分为轻度组(57例)与重度组(43例),按是否发生终点事件分为终点事件组(52例)与非终点事件组(48例),比较各组间sST2、N末端钠尿肽前体(NT-proBNP)、肌钙蛋白I(TnI)血清浓度水平。结果轻度组hs-CRP、肌酐、sST2、NT-proBNP及TNI均低于重度组,血红蛋白及LVEF高于重度组,差异有统计学意义(P<0.05)。重度组终点事件发生率高于轻度组,差异有统计学意义(χ2=8.855,P<0.05)。终点事件组hs-CRP、肌酐、sST2、NT-proBNP及TNI均高于非终点事件组,血红蛋白及LVEF低于非终点事件组,差异有统计学意义(P<0.05)。sST2预测病情程度和终点事件的ROC曲线下面积分别为0.697、0.732,NT-proBNP预测ROC曲线下面积分别为0.674、0.705,sST2与NT-proBNP联合预测病情程度和终点事件时ROC曲线下面积为分别为0.798、0.835。结论sST2对老年急性心力衰竭患者病情及预后均有良好评估价值,联合NT-proBNP时评估效能更佳。
出处 《中华保健医学杂志》 2019年第5期470-472,共3页 Chinese Journal of Health Care and Medicine
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