抑郁症相关疲劳感的研究进展

Research Progress on Depression Fatigue

疲劳感与抑郁症的关系十分复杂,其是抑郁症的一种常见症状;是一种普遍的抑郁症前驱症状,尤其是抑郁症首次发作时;也是抑郁症的一种残留症状,并且比其他抑郁症状更易趋于慢性化,与患者工作和社会功能缺损高度相关。因此,关注抑郁症患者的疲劳感症状对临床治疗抑郁症、改善患者的生活质量及降低复发率具有重要的临床意义。本文就抑郁症相关疲劳感的定义、临床表现、不良后果、产生机制、诊治进展进行综述,以期为广大医生提供参考。

The relationship between fatigue and depression is very complex.As a symptom of depression,fatigue is a common premonitory symptom especially at the first attack of the depression.Fatigue is also a residual symptom of depression which is more prone to become chronic disease than other depressive symptoms and is highly related to patients’ work and social function defects.Therefore,paying attention to fatigue of depressive patients has important significance for their clinical treatment,the improvement of their quality of life and the reduction of recurrence rate of depression.This article reviews the definition,clinical manifestation,adverse outcomes,mechanism,diagnosis and treatment of depression fatigue in order to provide a reference for doctors.