《2018多学科共识声明:成人糖尿病患者的预防接种》解读

Interpretation of Multi-disciplinary Consensus Statement Document Vaccinal Prevention in Adult Patients with Diabetes Mellitus

糖尿病是世界范围内的公共卫生问题之一,糖尿病慢性并发症所导致的发病率和死亡率增加,已经给社会、经济和医疗带来了巨大的负担.虽然有关糖尿病管理方面有许多指南出台,但对于成人糖尿病患者多种疫苗的预防接种,既往还没有共识/指南全面提及过.2018年意大利卫生、预防医学和公共卫生协会联合意大利医学糖尿病专家协会、意大利全科医生联合会、意大利糖尿病学会、意大利全科医学社团和初级保健学会共同发表了成人糖尿病患者的预防接种的多学科共识声明,即《2018多学科共识声明:成人糖尿病患者的预防接种》.这篇共识声明阐述了成人糖尿病患者易患感染的机制,以及流感疫苗、肺炎球菌疫苗、带状疱疹病毒疫苗、脑膜炎球菌疫苗、百日咳-白喉-破伤风疫苗等疫苗接种的意义和接种频率,并强调了糖尿病医师及全科医师在督导成人糖尿病患者进行疫苗接种中的重要作用.我国尚缺乏相应的临床指南或共识,但由于糖尿病患者越来越多,带来的卫生经济学负担越来越重,本文就意大利发表的这篇共识声明要点进行解读,旨在为我国成人糖尿病感染性疾病的预防接种政策制定及临床工作提供参考.

Diabetes is representatively one of the public health problems worldwide.The increasing morbidity and mortality due to chronic complications of diabetes has brought a huge burden to the society,national economy and public medical service.Although there are many guidelines for the management of diabetes,there is no consensus or guidelines for multiple vaccinations for adults with diabetes.In 2018 Italian Society of Hygiene,Preventive Medicine and Public Health,Italian Association of Medical Diabetologists,Italian Federation of General Practitioners,Italian Society of Diabetology and Italian Society of General Medicine & Primary Care jointly issued a multi-disciplinary consensus statement on vaccinations for adult diabetics Multi-disciplinary Consensus Statement Document Vaccinal Prevention in Adult Patients with Diabetes Mellitus.This consensus statement describes the mechanism of predisposition to infection in adults with diabetes,as well as the significance and frequency of flu vaccination,pneumococcal vaccination,anti-herpes zoster vaccination,meningococcal vaccination,and anti- diphteria-tetanus-pertussis vaccination.It highlights the important role of diabetes-treating physicians and general practitioners in supervising adults with diabetes for vaccination.There are still no corresponding clinical guidelines or consensus in China up to now,but due to the increasing number of patients with diabetes and the heavy burden of health economics,here this paper tries to interpret this consensus statement issued by Italy to provide references for the formulation of vaccination policy and clinical management for infectious diseases of adult diabetics in China.