产前超声联合MRI对胎儿中枢神经系统畸形的筛查价值

The Value of Prenatal Ultrasound Combined with MRI in Screening Fetal Central Nervous System Malformations

本文对产前超声联合核磁共振成像(MRI)筛查胎儿中枢神经系统(CNS)畸形的价值进行了分析。研究对象选取2016年1月~2019年2月本院收治的疑似胎儿CNS畸形的孕妇196例,所有孕妇均给予产前超声、MRI检查,以产后结果为对照,分析产前超声、MRI及二者联合对胎儿CNS畸形的筛查价值。结果显示,产后胎儿CNS畸形84例(42.86%);在筛查胎儿CNS畸形方面,产前超声敏感度、特异度、准确度分别为80.95%(68/84)、76.79%(86/112)、78.57%(154/196),产前MRI分别为88.10%(74/84)、82.14%(92/112)、84.69%(166/196),产前超声联合MRI分别为97.62%(82/84)、94.64%(106/112)、95.92%(188/196),产前超声联合MRI明显优于产前超声、MRI,差异有统计学意义(P<0.05)。产前超声与MRI比较,差异无统计学意义(P>0.05)。本文证实了产前超声、MRI对胎儿CNS畸形具有良好的筛查价值,且二者联合的筛查价值更高。

The value of prenatal ultrasound combined with magnetic resonance imaging(MRI)in screening fetal central nervous system(CNS)malformations was analyzed in this study.From January 2016 to February 2019,196 pregnant women suspected of fetal CNS malformation were selected as the subjects of study.All pregnant women were examined by prenatal ultrasound and MRI.The postpartum results showed that 84 cases(42.86%)had CNS malformation.The sensitivity,specificity and accuracy of the prenatal ultrasound in screening fetal CNS deformities were 80.95%(68/84),76.79%(86/112),78.57%(154/196),while the prenatal MRI were 88.10%(74/84),82.14%(92/112),84.69%(166/196).The sensitivity,specificity and accuracy of the prenatal ultrasound combined with MRI were 97.62%(82/84),94.64%(106/112),95.92%(188/196),which were significantly higher than single method,the difference was statistically significant(P<0.05).And there was no significant difference between prenatal ultrasound and MRI(P>0.05).This study confirms that prenatal ultrasound and MRI have the good screening value for fetal CNS malformation,and the combination of them has the higher screening value.