Er,Cr:YSGG激光联合盐酸米诺环素治疗慢性牙周炎的效果

Effect of Er,Cr:YSGG laser combined with Minocycline Hydrochloride in the treatment of chronic periodontitis

目的研究Er,Cr:YSGG激光联合盐酸米诺环素治疗慢性牙周炎的效果。方法选取2017年7月~2018年6月我院收治的86例慢性牙周炎患者作为研究对象,按照信封法随机分为对照组(43例)和实验组(43例)。对照组采用龈上洁治+龈下刮治+盐酸米诺环素治疗,实验组在对照组基础上给予Er,Cr:YSGG激光治疗。将两组的牙周指标、临床效果、炎症因子指标进行比较。结果实验组治疗后的牙周袋深度(PD)、牙龈出血指数(SBI)、菌斑指数(PLI)、附着丧失(AL)及C反应蛋白(CRP)、白介素-17(IL-17)均低于对照组,差异有统计学意义(P<0.05);实验组的临床总有效率高于对照组,差异有统计学意义(P<0.05)。结论采用Er,Cr:YSGG激光联合盐酸米诺环素治疗慢性牙周炎患者的效果确切,明显改善了牙周症状,有效减轻了炎症反应。

Objective To study the effect of Er,Cr:YSGG laser combined with Minocycline Hydrochloride in the treatment of chronic periodontitis.Methods A total of 86 patients with chronic periodontitis admitted to our hospital from July 2017 to June 2018 were selected and randomly divided into control group(43 cases)and experimental group(43 cases)according to envelope method.The control group was treated with supragingival scaling+subgingival curettage+Minocycline Hydrochloride,The experimental group was treated with Er,Cr:YSGG laser on the basis of the control group.The periodontal indexes,clinical effect and inflammatory factors were compared between the two groups.Results The periodontal pocket depth(PD),gingival bleeding index(SBI),plaque index(PLI),attachment loss(AL),C-reactive protein(CRP)and interleukin-17(IL-17)of the experimental group were lower than those of the control group after treatment,and the differences were statistically significant(P<0.05).The total clinical effective rate of the experimental group was higher than that of the control group,with statistical difference(P<0.05).Conclusion Er,Cr:YSGG laser combined with Minocycline Hydrochloride is effective in the treatment of chronic periodontitis,which can significantly improve periodontal symptoms and alleviate inflammation.