高分辨磁共振血管壁成像对高血压患者豆纹动脉血管特征分析的应用研究

Application of HR-MRI in characteristic analysis of lenticulostriate artery in patients with hypertension

目的探讨高分辨磁共振血管壁成像技术对高血压患者豆纹动脉(Lenticulostriate artery,LSA)数量及深度的特征分析。方法以2018年5月-2019年4月新疆医科大学第二附属医院影像中心收治的76名高血压患者为研究对象,根据中国老年高血压管理指南2019血压等级分为Ⅰ级(25例)、Ⅱ级(27例)、Ⅲ级(24例)高血压组,另取27名健康志愿者为对照组。对所有受试者行高分辨磁共振血管壁成像(High Resolution Magnetic Resonance Imaging,HR-MRI)3DT1WI-VISTA序列成像,受试者双侧豆纹动脉高分辨血管成像数据传至后处理工作站,应用Philips Intellispace portal软件对的血管数量及深度进行统计,采用SPSS 22.0软件对4组受试者双侧豆纹动脉的深度及数目进行统计学分析。结果与对照组比较,各级高血压组组间一般资料差异均无统计学意义(P>0.05)。与对照组比较,Ⅰ级高血压组患者双侧豆纹动脉深度和数目差异无统计学意义(P>0.05);Ⅱ、Ⅲ级高血压组患者双侧豆纹动脉的深度和数目降低,差异有统计学意义(P<0.01)。结论高分辨磁共振血管壁成像对豆纹动脉血管特征分析具有临床价值,Ⅱ、Ⅲ级高血压患者的双侧豆纹动脉的数量及深度低于正常人群。

Objective To explore the value of HR-MRI in the study of the number and depth of lenticular artery in patients with hypertension.Methods A total of 76hypertensive patients admitted to the Imaging Center of the Second Affiliated Hospital of Xinjiang Medical University from May 2018 to April 2019 were studied.According to the blood pressure level grades in the Chinese Guidelines for the Management of Senile Hypertension in 2019,they were divided into the first grade(25cases),the second grade(27cases) and the third grade(24cases)hypertension groups.Twenty-seven healthy volunteers were selected as the control group.High Resolution Magnetic Resonance Imaging(HR-MRI)and 3D-T1WI-VISTA sequence imaging were performed in all subjects.The number and depth of blood vessels were analyzed by Philips Intellispace portal software at the data transmitter workstation of high resolution arteriography of lenticulostriate arteries in all subjects.Results Compared with the control group,there was no significant difference in the general data between the hypertension groups at all levels(P>0.05).Compared with the control group,there was no significant difference in the depth and number of bilateral lenticular arteries between the first grade hypertension group and the control group(P>0.05).The depth and number of bilateral striated lenticular arteries in patients with the second-grade and the third-grade hypertension were decreased,and the difference were statistically significant(P<0.01).Conclusion HR-MRI is of clinical value in the analysis of arterial characteristics of lenticulostriate artery.The number and depth of bilateral lenticulostriate arteries in patients with the second grade and the third grade hypertension are lower than those in normal subjects.