胃癌患者术后口服化疗药依从性与服药信念的相关性调查研究

The association between medication compliance and belief on oral chemotherapeutic drugs in patients with postoperative gastric cancer

目的明确胃癌患者术后口服化疗药的服药依从性与服药信念的关系,为干预措施提供理论依据。方法采用方便抽样法抽取219名胃癌术后口服化疗药患者,分别使用一般情况调查问卷、Morisky服药依从性问卷、服药信念量表(BMQ)进行调查,并应用SPSS19.0进行数据统计分析。结果胃癌术后口服化疗药的患者服药信念普适性维度得分为(13.37±5.36)分,必要性感知维度得分为(9.97±4.71)分,服药导致不良反应的顾虑维度得分为(5.38±2.65)分;服药依从性得分为(5.83±2.14)分,服药信念与服药依从性Pearson相关系数为0.577,各维度之间及各维度与总问卷的Pearson相关系数为0.411~0.457。结论服药信念越强者依从性越好,因而可以通过健康教育等形式帮助患者树立和强化服药信念,进而提高其服药依从性,最终达到保证治疗效果的目的。

Objective The aim of this study is to elucidate the association between medication compliance and belief on oral chemotherapeutic drugs in patients with postoperative gastric cancer, and to provide theoretical basis for intervention measures. Methods A total of 219 cases undergoing oral chemotherapy after surgery for gastric cancer were enrolled by convenient sampling method into our study.The general information questionnaire, Morisky medication adherence scale(MMAS) questionnaire and beliefs about medicines questionnaire(BMQ) were used in the survey.Data were analyzed using SPSS19.0 software. Results Among patients with postoperative oral chemotherapy for gastric cancer, the scores of universality belief dimension, necessity perception dimension, concern dimension about adverse effects of drugs and compliance dimension were 13.37 ± 5.36, 9.97 ± 4.71, 5.38 ± 2.65 and 5.83 ± 2.14, respectively.Pearson correlation coefficient between belief and compliance was 0.577.The Pearson correlation coefficients between each dimension and the total questionnaire ranged from 0.411 to 0.457. Conclusions Patients who have stronger beliefs on medication usually have better compliances on drugs.Therefore, health education should be strengthened to help patients establish higher beliefs about medicines in order to improve their compliances on oral chemotherapy and to guarantee the therapeutic effect.