摘要
自身免疫性多内分泌腺病综合征(APS)即同一患者同时或先后出现2种或2种以上内分泌腺自身免疫疾病。本文报道于2018-07-10入住南京中医药大学附属中西医结合医院1例甲状腺功能亢进(Graves病)合并1型糖尿病的APSⅡ型患儿。患儿为12岁女性,因颈前肿大伴双眼突出6年就诊,多年抗甲状腺药物治疗甲状腺功能亢进及突眼效果差,病程中伴发1型糖尿病。予以甲状腺切除术,并以胰岛素控制1型糖尿病,使得甲状腺功能亢进、甲状腺相关性眼病、1型糖尿病得以良好控制。
Autoimmune polyendocrinopathy syndrome(APS) refers to a group of syndromes comprising two or more kinds of endocrine autoimmune diseases.We reported a case with APS type Ⅱ combined with Graves disease and type 1 diabetes who admitted to Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine on 10 July 2018.A 12-year-old girl had enlarged neck mass and exorbitsm for 6 years.Antithyroid drugs had poor therapeutic effects,and type 1 diabetes was confirmed in the course of disease.Thyroidectomy and insulin control of type 1 diabetes mellitus can control hyperthyroidism,thyroid-associated ophthalmopathy and type 1 diabetes mellitus.
作者
相萍萍
苏晓辉
狄红杰
刘超
曹雯
XIANG Pingping;SU Xiaohui;DI Hongjie;LIU Chao;CAO Wen(Department of Endocrinology,Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210028,China;Key Research Laboratory of Gall Disease Syndrome and Treatment,Jiangsu Province Academy of Traditional Chinese Medicine,Nanjing 210028,China;Xinyi Central Hospital,Xinyi 221400,China)
出处
《中国全科医学》
CAS
北大核心
2019年第35期4401-4405,共5页
Chinese General Practice
基金
国家自然科学基金面上基金（81471010）
国家中医药管理局重大疑难疾病中西医临床协作试点项目瘿气（Graves病、甲状腺机能亢进症）（2018）
