That’s A Scientist Should Do——A Dialog with Tomas Lindahl

That’s A Scientist Should Do——A Dialog with Tomas Lindahl

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摘要 Dr Tomas Lindahl is a world-renowned scientist specialized in cancer research,in particular,DNA repair[1].In 2015,he was awarded the Nobel Prize in Chemistry jointly with Dr Paul L.Modrich and Dr Aziz Sancar“for mechanistic studies of DNA repair”(https://www.nobelprize.org/prizes/chemistry/2015/press-release/)[2].During his recent visits in China,besides delivering lectures,Tomas also attended a couple of group meetings with students and PIs.He actively interacted with the audience,not only on topics relating to DNA repair,but also on how to do science and beyond.We presented this special report based on recordings.

作者 Shanshan Xie Yuxia Jiao

机构地区 Beijing Institute of Genomics

出处《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2019年第3期223-225,共3页 基因组蛋白质组与生物信息学报（英文版）

关键词 LINDA jointly specialized

分类号 G32 [文化科学]

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1Arne Klungland,Yun-Gui Yang.Endogenous DNA Damage and Repair Enzymes—A short summary of the scientific achievements of Tomas Lindahl,Nobel Laureate in Chemistry 2015[J].Genomics, Proteomics & Bioinformatics,2016,14(3):122-125. 被引量：2

二级参考文献34

1Lindahl T, Nyberg B. Rate of depurination of native deoxyri- bonucleic acid. Biochemistry 1972;11:3610 8.
2Karran P, Lindahl T. Hypoxanthine in deoxyribonucleic acid: generation by heat-induced hydrolysis of adenine residues and release in free form by a deoxyribonucleic acid glycosylase from calf thymus. Biochemistry 1980;19:6005 11.
3Rydberg B, Lindahl T. Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction, EMBO J 1982;1:211-6.
4Breimer LH, Lindahl T. Thymine lesions produced by ionizing radiation in double-stranded DNA. Biochemistry 1985;24: 4018 22.
5Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993;362:709-15.
6Lindahl T. New class of enzymes acting on damaged DNA. Nature 1976;259:64 6.
7Lindahl T. An N-glycosidase from Escherichia coil that releases free uracil from DNA containing deaminated cytosine residues. Proc Natl Acad Sci U S A 1974;71:3649-53.
8Chetsanga C J, Lindahl T. Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli. Nucleic Acids Res 1979;6:3673 84.
9Roldfin-Arjona T, Wei YF, Carter KC, Klungland A, Anselmino C, Wang RP. Molecular cloning and functional expression of a human eDNA encoding the antimutator enzyme 8-hydroxygua- nine-DNA glycosylase. Proc Natl Acad Sci U S A 1997;94: 8016-20.
10Dianov G, Price A, Lindahl T. Generation of single-nucleotide repair patches following excision of uracil residues from DNA. Mol Cell Biol 1992;12:1605-12.

共引文献1

1Jiadong Wang,Tomas Lindahl.Maintenance of Genome Stability[J].Genomics, Proteomics & Bioinformatics,2016,14(3):119-121.

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That’s A Scientist Should Do——A Dialog with Tomas Lindahl

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