不同血型术后感染患者炎症水平及病原菌分布研究

Study on inflammation level and pathogenic bacteria distribution in postoperative infection patients with different blood groups

目的探究不同血型术后感染患者炎症水平及病原菌分布研究,为制定针对性预防措施提供依据。方法回顾性分析2016年2月~2018年2月148例于本院收治的术后感染患者的临床资料,其中A血型46例,B血型35例,AB血型15例,O血型52例,检测患者常规炎症指标水平及病原菌,并对比不同血型患者术后各炎症水平,分析病原菌分布情况。结果不同血型组间白细胞计数、中性粒细胞比例、C反应蛋白及白介素-2比较差异有统计学意义(P<0.05),其中A血型组各水平较其他组明显升高(P<0.05);167株病原菌中革兰阴性菌92株(55.09%),革兰阳性菌71株(42.51%),真菌4株(2.40%);不同血型组间革兰阴性菌、革兰阳性菌比较差异有统计学意义(P<0.05),其中A血型铜绿假单胞菌、金黄色葡萄球菌、粪肠球菌检出率均较其他组高(P<0.05)。结论不同血型术后感染患者炎症水平及病原菌分布均不同,其中A血型患者易受病菌感染,因此临床应根据病原菌感染情况,重点监控A血型患者,积极采取预防措施控制感染。

Objective To explore the level of inflammation and distribution of pathogenic bacteria in patients with post-operative infections of different blood groups,so as to provide basis for formulating targeted preventive measures.Methods Retrospective analysis of clinical data of 148 patients with post-operative infections admitted to our hospital from February 2016 to February 2018,including 46 cases of blood group A,35 cases of blood group B,15 cases of blood group AB and 52 cases of blood group O,the routine inflammation index and pathogenic bacteria of patients were detected,and the inflammation levels of patients with different blood groups were compared,and the distribution of pathogenic bacteria was analyzed.Results There were significant differences in white blood cell count,neutrophil ratio,C-reactive protein and interleukin-2 between different blood groups,and the levels of A blood group were significantly higher than those of other groups(P<0.05);among 167 pathogenic bacteria,92 were gram-negative(55.09%),71 were Gram-positive(42.51%)and 4 were fungi(2.40%);there were significant differences in Gram-negative bacteria and Gram-positive bacteria among different blood groups.The detection rates of Pseudomonas aeruginosa,Staphylococcus aureus and Enterococcus faecalis in A blood group were higher than those in other groups(P<0.05).Conclusions Inflammation level and pathogenic bacteria distribution in patients with different blood group post-operative infections are different,patients with blood group A are susceptible to pathogenic bacteria infection.Therefore,clinical monitoring of patients with blood group A should focus on pathogenic bacteria infection,and active preventive measures should be taken to control infection.