外泌体在口腔组织发育和再生研究新进展

Recent Advancement in Development and Regeneration of Exosomes in Oral Tissues

外泌体(exosome)是细胞外囊泡亚组份,作为纳米级信号分子在细胞、组织和器官之间传递生物分子信息,促进机体血管再生、损伤组织修复。而在口腔中,外泌体不仅可以调控牙、骨、唾液腺等组织发生发育,还可以促进颌面组织创伤修复和牙髓、牙周组织再生。本文将对外泌体在口腔组织发育和再生中的作用研究新进展做一综述。

Exosomes secreted by cells are small vesicles.As a nanoscale signal molecule,exosomes play a key role in the communication among cells,tissue,and organs.Recently,studies demonstrate that exosomes can promote angiogenesis,wound healing,and bone regeneration.This paper reviewed relevant studies about the effect of exosomes on promting the organogenesis and regeneration of oral tissue.