痛风灵汤对痛风性关节炎患者疼痛程度及炎症反应的影响

Influence of Tongfengling decoction on pain degree and inflammatory response in patients with gouty arthritis

目的探讨痛风灵汤对痛风性关节炎患者疼痛程度及炎症反应的影响。方法选择2017年1月—2019年2月本院收治的痛风性关节炎患者63例,根据随机数字表法分为对照组(31例)和观察组(32例)。两组患者均给予常规治疗,对照组在常规治疗基础上给予英太青治疗,观察组在常规治疗基础上给予痛风灵汤治疗,比较两组患者的疼痛程度、炎症反应指标及不良反应发生情况。结果治疗后,观察组视觉模拟评分法(visual analogue scale,VAS)评分低于对照组,差异有统计学意义(P<0.05);观察组血沉、超敏C反应蛋白水平低于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论痛风灵汤治疗痛风性关节炎患者安全性高,能有效降低患者疼痛程度,减轻炎症反应。

Objective To investigate the influence of Tongfengling decoction on pain degree and inflammatory response in patients with gouty arthritis.Methods 63 patients with gouty arthritis who admitted in the hospital from January 2017 to February 2019 were selected as research subjects.All selected cases were divided into control group(31 cases)and observation group(32 cases)according to the random number table.The patients in two groups were given routine treatment.Control group was given diclofenac based on routine treatment,and observation group was treated with Tongfengling decoction based on routine treatment.The pain degree,inflammatory response indexes,and adverse reactions were compared between the two groups.Results After treatment,the score of Visual Analogue Scale(VAS)in observation group was lower than that in control group,and the difference was statistically significant(P<0.05);The levels of erythrocyte sedimentation rate and high-sensitivity C-reactive protein in observation group were lower than those in control group,and the difference was statistically significant(P<0.05);The incidence of adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion Tongfengling decoction in treatment of patients with gouty arthritis has high safety,it can effectively decrease pain degree and reduce inflammatory response.