摘要
电针预处理可减轻脑缺血后神经缺损程度,发挥脑保护效应,机制可能涉及调节内源性大麻素系统、抑制兴奋毒性、抑制氧化应激、抑制内质网应激、抑制炎症反应、保护血脑屏障、抑制细胞凋亡和调节自噬等多个方面。
Electroacupuncture preconditioning can alleviate the nerve defect after cerebral ischemia injury, induce cerebral ischemic tolerance and exert the certain protective effect on brain, which may be involved in regulating endocannabinoid system, inhibiting exitotoxicity, inhibiting oxidative stress, inhibiting endoplasmic reticulum stress, inhibiting inflammatory response, protecting blood-brain barrier, inhibiting apoptosis and regulating autophagy, etc.
作者
宁文华
李礼
郭扬
张宝瑜
王洋
赵梦雄
王舒
NING Wen-hua;LI Li;GUO Yang;ZHANG Bao-yu;WANG Yang;ZHAO Meng-xiong;WANG Shu(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China;Tianjin Key Laboratory of Acupuncture and Moxibustion,Tianjin 300381,China;Key Laboratory of Acupuncture and Moxibustion Encephalopathy,State Administration of Traditional Chinese Medicine,Tianjin 300381,China)
出处
《中国康复理论与实践》
CSCD
北大核心
2019年第11期1315-1319,共5页
Chinese Journal of Rehabilitation Theory and Practice
基金
国家自然科学基金项目(No.81804189)
长江学者和创新团队发展计划项目(No.IRT1167)
天津市卫生和计划生育委员会中医、中西医结合科研专项课题(No.2017130)
天津市教委科研计划项目(No.2018KJ020)~~
关键词
缺血性脑卒中
电针预处理
脑缺血耐受
脑保护
综述
ischemic stroke
electroacupuncture preconditioning
brain ischemic tolerance
brain protective
review
