高通量血液透析治疗对维持性血液透析患者心功能指标影响

Effect of High-Throughput Hemodialysis on Cardiac Function in Maintenance Hemodialysis Patients

目的分析高通量血液透析治疗对维持性血液透析患者心功能指标影响。方法选取贵阳市第二人民医院2016年8月至2017年8月进行维持性血液透析治疗患者90例进行研究,通过计算机随机编组方式将患者分为普通组和高通量组,各45例,分别实行普通血液透析治疗和高通量血液透析治疗,比较两组患者治疗效果。结果经过治疗后,高通量组患者血红蛋白(Hb)、白蛋白(Alb)、全段甲状旁腺激素(iPTH)、C-反应蛋白(CRP),均低于普通组患者(P<0.05);高通量组患者左室收缩末期内径(LVESD)(28.68±2.31)mm、左室舒张末期内径(LVEDD)(46.38±4.16)mm、EF(57.45±3.89)%、CI(3.26±0.25)L/min·m2、E/A(1.18±0.24)mm,均高于普通组患者(P<0.05)。结论对维持性血液透析患者采取高通量血液透析治疗效果高于普通血液透析治疗,能有效改善Hb、Alb、β2-MG等生化指标,清除毒素,改变炎症状态,改善患者心功能指标。

Objective To analyze the effect of high flux hemodialysis on cardiac function in maintenance hemodialysis patients.Methods Ninety patients with maintenance hemodialysis in our hospital from August 2016 to August 2017 were selected for the study.The patients were randomly divided into two groups:the normal group and the high-throughput group(each 45 cases).They were treated with general hemodialysis and high-throughput hemodialysis respectively.The therapeutic effects of the two groups were compared.Results After treatment,Hb,Alb,iPTH and CRP in high-throughput group were lower than those in normal group(P<0.05);LVESD(28.68±2.31)mm,LVEDD(46.38±4.16)mm,EF(57.45±3.89)%,CI(3.26±0.25)L/min.m2,E/A(1.18±0.24)mm in high-throughput group were better than those in general group(P<0.05).Conclusion High flux hemodialysis is superior to conventional hemodialysis in the treatment of maintenance hemodialysis patients.It can effectively improve biochemical indicators such as Hb,Alb and beta 2-MG,and improve the cardiac function of patients.