CPAP对新生儿呼吸窘迫综合征中的效果及并发症影响

Effect of CPAP on Neonatal Respiratory Distress Syndrome and Its Complications

目的探究持续气道正压(CPAP)在新生儿呼吸窘迫综合征中的效果及并发症情况。方法选取2017年2月至2019年2月常州市儿童医院收治的130例新生儿呼吸窘迫征患儿,采用随机数字法分为两组,每组65例。对照组患儿头罩吸氧治疗,实验组患儿实施CPAP给氧治疗。比较两组患儿治疗前后血气分析情况、治疗有效率以及并发症情况。结果4治疗6、12、24 h后,实验组患儿血氧饱和度(TcSO2)、动脉血氧分压(PaO2)明显高于对照组,二氧化碳分压(PaCO2)明显低于对照组,差异均有统计学意义(P<0.05)。实验组治疗有效率明显高于对照组(89.23% vs.44.62%),并发症发生率明显低于对照组(10.77% vs.18.46%),差异均有统计学意义(P<0.05)。结论针对新生儿呼吸窘迫综合征患儿,采用CPAP给氧治疗能够提高治疗效果,减少并发症的发生。

Objective To explore the effect of CPAP on neonatal respiratory distress syndrome and its complications.Methods One hundred and thirty neonates with respiratory distress syndrome who were treated in our hospital from February 2017 to February 2019 were selected and divided into two groups by a random number method,65 cases per group.The control group were given oxygen by hood,while the experimental group were given oxygen by CPAP.The blood gas analysis,treatment efficiency and complications of the two groups before and after treatment were compared.Results After 6,12 and 24 h of treatment,TcSO2 and PaO2 in the experimental group were significantly higher than those in the control group,and PaCO2 was significantly lower than that in the control group(P<0.05).The effective rate in the control group was significantly higher than that in the control group(89.23% vs.44.62%,P<0.05),while the complication rate was significantly lower than that in the control group(10.77% vs.18.46%,P<0.05).Conclusion For neonatal respiratory distress syndrome,CPAP oxygen therapy can improve the therapeutic effect and reduce the incidence of complications.