降钙素原在儿童呼吸道感染中的临床意义

Clinical Significance of Procalcitonin in Children with Respiratory Tract Infection

目的研究降钙素原(PCT)在儿童呼吸道感染中的临床意义。方法选取2017年12月至2018年12月菏泽市牡丹人民医院行呼吸道感染患者中选取116例为本研究对象,根据病情诊断结果分至观察组和对照组,各58例。观察组均为细菌感染患儿,对照组均为病毒感染患儿。全体患者均于入院诊治前、诊治第4天及第7天时行1 mL静脉血收集,送检。比较两组患者PCT阳性率及诊治前后PCT值。结果观察组PCT阳性率为93.10%(54/58),明显高于对照组的17.24%(10/58),差异有统计学意义(P<0.05)。诊治后观察组PCT水平较诊治前明显下降,差异有统计学意义(P<0.05),而对照组PCT水平同诊治前比较差异无统计学意义(P>0.05)。结论PCT为判断儿童呼吸道病毒感染、细菌感染的一类敏感指标,为早期诊治提供参考,具备重要临床意义。

Objective To study the clinical significance of procalcitonin(PCT)in respiratory tract infection in children.Methods From December 2017 to December 2018,116 children of respiratory tract infection were selected as the subjects,and divided into the control group and observation group according to the diagnosis results,58 cases per group.The observation group were all children with bacterial infection,the control group were children with virus infection.All patients received 1 mL vein blood collection before admission for diagnosis and treatment,4 and 7 days after diagnosis and treatment,respectively,The PCT positive rate and PCT value before and after the diagnosis and treatment of the two groups were compared.Results The PCT positive rate was 93.10%(54/58)in the observation group,significantly higher than that in the control group(17.24%,10/58,P<0.05).After treatment,the PCT content of the observation group was decreased compared with that before treatment(P<0.05).There was no significant difference in the control group between and after treatment(P>0.05).Conclusion PCT,as a kind of sensitive index to judge respiratory virus infection and bacterial infection in children,can provide reference for early diagnosis and treatment,and has important clinical significance.