小儿肺炎支原体感染临床检验的诊断价值分析

Diagnostic Value of Clinical Examination of Children with Mycoplasma Pneumoniae Infection

目的探讨小儿肺炎支原体感染疾病临床检验的诊断价值,用于减少临床误诊、漏诊率。方法方便选取该院儿科于2018年9月-2019年1月的120例肺炎支原体感染患儿,所有患儿入院后,均进行临床常规化验(血常规、血沉、C-反应蛋白),免疫学检查[酶联免疫吸附法测肺炎支原体特异性免疫球蛋白M(MP-IgM)、冷凝集试验],微生物快速培养法检测,根据临床检验结果,对比正常值进行分析探讨。结果患儿白细胞计数>10.0×10^9/L的比例为48.3%与白细胞(4.0~10.0)×10^9/L的比例40.8%对比,差异无统计学意义(P>0.05),与白细胞<4.0×10^9/L(10.8%)对比,差异有统计学意义(P<0.05),血小板计数>100×10^9/L的比例为80.0%与<100×109/L的比例20.0%对比,血沉升高的比例为69.2%与正常比例30.8%对比;C-反应蛋白升高的比例为64.2%与正常的比例35.8%对比,均差异有统计学意义(P<0.05);MPIgM阳性的比例87.5%、冷凝集试验的比例76.8%以及微生物培养阳性的比例30.8%两两对比,差异有统计学意义(P<0.05)。结论只有在结合多种临床检验技术并根据结果进行分析,才能提高确诊率,减少误诊和漏诊率,在早期为患儿确诊病原体并及时给予对应的治疗方案,对提高临床救治率有重要意义。

Objective To investigate the diagnostic value of clinical examination of children with Mycoplasma pneumoniae infection, and to reduce the rate of clinical misdiagnosis and missed diagnosis. Methods A total of 120 children with mycoplasma pneumoniae infection were enrolled in the hospital from September 2018 to January 2019. All patients were convenient admitted to the hospital for clinical routine tests(blood routine, erythrocyte sedimentation rate, C-reactive protein),immunological examination.(Enzyme-linked immunosorbent assay for detection of Mycoplasma pneumoniae-specific immunoglobulin M(MP-IgM), condensation set test), microbial rapid culture method detection, according to clinical test results, compared with normal values for analysis and discussion. Results The ratio of white blood cell count >10.0×10^9/L was48.3% compared with 40.8% of white blood cells(4.0-10.0)×10^9/L. The difference was not statistically significant(P>0.05),and white blood cells <4.0×10^9/L 10.8%, the difference was statistically significant(P<0.05), the ratio of platelet count>100×10^9/L was 80.0% and the ratio of platelet count<100×10^9/Lwas 20.0%. The ratio of elevated erythrocyte sedimentation rate was 69.2% and the normal ratio was 30.8%;the ratio of C-reactive protein elevation was 64.2% compared with the normal ratio of 35.8%, the difference was statistically significant(P<0.05);the proportion of MP-IgM positive was 87.5%, the proportion of condensation set test was 76.8%, and The proportion of positive microbial culture was 30.8%, and the difference was statistically significant(P <0.05). Conclusion As long as the combination of multiple clinical testing techniques and analysis based on the results, can improve the diagnosis rate, reduce the rate of misdiagnosis and missed diagnosis, and diagnose the pathogens in the early stage and timely give corresponding treatment plans, which is of great significance to improve the clinical treatment rate.