布地奈德联合特布他林雾化吸入治疗儿童毛细支气管炎的临床疗效

Clinical Effect of Atomized Inhalation of Budesonide Combined with Terbutaline in the Treatment of Children with Bronchiolitis

目的 探讨布地奈德与特布他林雾化吸入治疗儿童毛细支气管炎的临床疗效。方法 选取2017年2月至2019年2月西安航空发动机(集团)有限公司职工医院收治的82例毛细支气管炎患儿,按信封法分为对照组(基础治疗+特布他林雾化吸入)与研究组(基础治疗+布地奈德联合特布他林雾化吸入),每组41例。比较两组临床疗效及治疗前后白细胞计数(WBC)、中性粒细胞计数(NEU)和C反应蛋白(CRP)水平。结果 研究组患儿临床总有效率明显高于对照组,差异有统计学意义(97.56%vs. 80.49%,P <0.05)。两组治疗后白细胞计数(WBC)、中性粒细胞计数(NEU)和CRP均较本组治疗前明显下降,差异有统计学意义(P <0.05),且研究组均明显低于对照组(P <0.05)。结论 对毛细支气管炎患儿给予布地奈德联合特布他林雾化吸入可显著改善临床疗效及实验室指标。

Objective To investigate the clinical effect of atomized inhalation of budesonide combined with terbutaline in the treatment of children with bronchiolitis.Methods From February 2017 to February 2019,82 children with bronchiolitis in Xi'an Aero Engine(Group)Co.,Ltd.Staff Hospital were divided into a control group(basic treatment+terbutaline atomized inhalation)and a research group(basic treatment+atomized inhalation of budesonide combined with terbutaline)according to the envelope method,41 patients in each group.The clinical effect and the white blood cell count(WBC),neutrophil count(NEU),and C-reactive protein(CRP)before and after treatment of the two groups were compared.Results The total effective rate in the research group was significantly higher than that in the control group(97.56%vs.80.49%,P<0.05).Compared with those before treatment,the WBC,NEU and CRP were all decreased after treatment in both groups(P<0.05),and the research group was significantly lower than the control group(P<0.05).Conclusion Atomized inhalation of budesonide combined with terbutaline can significantly improve the clinical effect and laboratory indicators of children with bronchiolitis.