无创双水平正压通气治疗新生儿呼吸窘迫综合征的临床研究

Clinical Study of Noninvasive High Frequency Ventilation in the Treatment of NeonatalRespiratory Distress Syndrome

目的观察无创双水平正压通气治疗新生儿呼吸窘迫综合征临床研究。方法选取2015年6月至2018年6月成都市成华区妇幼保健院收治的72例新生儿呼吸窘迫症患者为研究对象,将其分为两组,每组36例。对照组应用常规化治疗,观察组在对照组基础上接受无创双水平正压辅助治疗。对比两组治疗效果。结果干预前,两组受试者的二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)以及平均动脉压(MAP)、氧气吸乳浓度(FiO2)、氧指数(OI)等指标无明显差异(P>0.05)。干预后,观察组相关指标改善情况显著优于对照组(P<0.05)。结论在常规治疗基础开展无创双水平正压通气治疗重症新生儿呼吸窘迫症,能够取得满意效果。

Objective To observe the clinical study of non-invasive double-level positive pressure ventilation in the treatment of respiratory distress syndrome(RDS).Methods In this study,72 patients with respiratory distress were treated in Chengdu Chenghua District Maternal and Child Health Hospital in June of 2015 and June of 2018,and were divided into two groups(36 cases in each group).The control group should be treated with routine therapy,and the observation group was treated with non-invasive double-level positive pressure on the basis of the control group.The therapeutic effects of the two groups were compared.Results Before preconditioning,the partial pressure of oxycarbon peroxide(PaCO2),the partial pressure of arterial oxydol(PaO2),the mean arterial pressure(MAP),the concentration of oxydol(FiO2),and oxygen index(OI)and other indexes in the two groups were not significantly different(P>0.05).The improvement of prognosis and related indexes in the observation group was significantly better than that in the control group(P<0.05).Conclusion The non-invasive double-level positive pressure therapy can achieve satisfactory results in the treatment of severe neopterus respiratory distress.