盐酸米诺环素联合替硝唑治疗牙周炎的疗效

Effect of Minocycline Hydrochloride Combined with Tinidazole on Periodontitis

目的分析牙周炎采用盐酸米诺环素联合替硝唑治疗的疗效。方法选取2016年1月至2019年1月赤峰学院附属医院收治的150例胃热型牙周炎患者为研究对象,按就诊顺序将其分为两组,每组75例。对照组单纯使用替硝唑治疗,观察组应用盐酸米诺环素联合替硝唑治疗。比较两组患者治疗有效率及治疗前后牙龈出血指数(GI)、牙齿松动度(MD)、牙周袋深度(PPD)、牙周附着水平(PAL)以及牙菌斑指数(PLI)。结果观察组总有效率明显高于对照组(96.00%vs.80.00%,P<0.05)。治疗前两组受试者GI、MD、PPD、PAL、PLI比较无明显差异(P>0.05)。治疗后,观察组GI、MD、PPD、PAL、PLI明显低于对照组(P<0.05)。结论盐酸米诺环素联合替硝唑治疗牙周炎患者,能够取得满意效果。

Objective To analyze the effect of minocycline hydrochloride combined with tinidazole on periodontitis.Methods From January 2016 to January 2019,150 cases of periodontitis with Wei(Stomach)heat syndrome admitted to our hospital were selected as subjects,and divided into two groups according to the registration order,75 cases in each group.The control group was treated with tinidazole alone,while the observation group was treated with minocycline hydrochloride combined with tinidazole.The effective rates of treatment as well as GI,MD,PPD,PAL and PLI in the two groups were compared.Results The effective rate of treatment was significantly increased in the observation group compared with the control group(96.00%vs.80.00%,P<0.05).Before intervention,there was no significant difference in GI,MD,PPD,PAL and PLI between the two groups(P>0.05).After the intervention,compared with the control group,the GI,MD,PPD,PAL and PLI in the observation group were significantly decreased(P<0.05).Conclusion For patients with chronic periodontitis,minocycline hydrochloride combined with tinidazole can achieve satisfactory results.