阿司匹林联合氯吡格雷对脑梗死的临床治疗效果

EClinical Effect of Aspirin Combined with Clopidogrel on Cerebral Infarction

目的观察脑梗死选择阿司匹林联合氯吡格雷治疗的临床疗效。方法选取2017年5月至2018年7月江苏省溧阳市中医院接诊的92例脑梗死患者作为观察对象,根据硬币法分为对照组和治疗组,各46例。对照组给予阿司匹林治疗,治疗组给予阿司匹林联合氯吡格雷治疗。比较两组临床疗效、治疗前后神经功能缺损评分(NIHSS)变化。结果治疗组治疗总有效率显著高于对照组,组间差异有统计学意义(P<0.05);治疗后两组NIHSS评分均显著低于治疗前,且治疗组低于对照组,组间具有明显差异(P<0.05)。结论脑梗死采用阿司匹林、氯吡格雷联合治疗方案,可进一步提高临床疗效,改善神经功能。

Objective To observe the clinical efficacy of aspirin combined with clopidogrel in the treatment of cerebral infarction.Methods A total of 92 patients with cerebral infarction who were admitted to our hospital from May 2017 to July 2018 were selected as observation subjects.They were divided into control group and treatment group according to the coin method,46 cases in each group.The control group was treated with aspirin alone.The treatment group was treated with aspirin plus clopidogrel,and the clinical efficacy and neurological deficit scores(NIHSS)before and after treatment were compared between the two groups.Results The total effective rate of the treatment group was significantly higher than that of the control group(P<0.05).After treatment,the scores of NIHSS in the two groups were significantly lower than those before treatment,and those in the treatment group were significantly lower than those in the control group(P<0.05).Conclusion Intracerebral infarction combined with aspirin and clopidogrel in the treatment of cerebral infarction can further improve clinical efficacy and improve neurological function.