2型糖尿病合并高脂血症患者调脂药物服药依从性现状及影响因素分析

Adherence to Lipid-Regulating Medications in Patients with Type 2 Diabetes Mellitus Complicated with Hyperlipidemia and Influencing Factors

目的探讨2型糖尿病合并高脂血症患者调脂药物服药依从性现状及影响因素。方法选取2型糖尿病合并高脂血症620例作为研究对象,对其调脂药物服药依从性及一般资料等进行调查分析,并采用单因素和多因素分析影响2型糖尿病合并高脂血症患者调脂药物服药依从性因素。结果 2型糖尿病合并高脂血症620例调脂药物服用依从性好302例(48.71%),依从性差318例(51.29%)。依从性差者未婚、受教育程度为高中及以下、居住方式为未与家人住、无糖尿病教育、病程≥10年占比较依从性好者明显高,且经济收入较依从性好者明显低,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,未婚、受教育程度低、经济收入低、未与家人住、无糖尿病教育及病程≥10年是影响2型糖尿病合并高脂血症患者调脂药物服药依从性的危险因素(P<0.05)。结论 2型糖尿病合并高血脂血症患者调脂药物服药依从性现状不容乐观,其中婚姻状况、受教育程度、经济收入、是否与家人住、有无接受糖尿病教育以及病程都是2型糖尿病合并高脂血症患者调脂药物服药依从性的影响因素。

Objective To investigate the adherence to lipid-regulating medications in patients with type 2 diabetes mellitus(T2DM) complicated with hyperlipidemia and influencing factors. Methods A total of 620 patients with T2DM complicated with hyperlipidemia were selected as the study subjects. The adherence to lipid-regulating medications, and general information were investigated and analyzed. Univariate and multivariate analyses were performed to analyze factors affecting the adherence to lipid regulating medications in T2DM patients complicated with hyperlipidemia. Results In the 620 patients with T2DM complicated with hyperlipidemia, there were 302 cases(48.71%) with good medication adherence and 318 cases(51.29%) with poor medication adherence. The proportions of unmarried patients, those with education level of high school or lower, those not living with family members, those without education on diabetes and those with a disease course of 10 years or longer were significantly higher in patients with poor medication adherence than in patients with good medication adherence. In addition, the economic income was significantly less than patients with good medication adherence(P<0.05). Logistic regression analysis showed that unmarried status, low educational level, low income, not living with family members, no education on diabetes and disease course of 10 years or longer were risk factors affecting the adherence to lipid-regulating medications in T2DM patients complicated with hyperlipidemia(P<0.05). Conclusion The adherence to lipid-regulating medications in T2DM patients complicated with hyperlipidemia is not optimistic. The marital status, education level, economic income, whether they live with their family members, whether they receive education on diabetes and the course of the disease are influencing factors of adherence to lipid-regulating medications in T2DM patients complicated with hyperlipidemia.