炎性肠病相关的神经影像研究进展

Advances in neuroimaging of inflammatory bowel disease

炎性肠病是一类由多种病因引起的肠道慢性及复发性炎症性疾病,具有终身复发的倾向。除了已知的关节炎、虹膜炎等肠道外症状,有研究指出,炎性肠病患者还存在神经系统受累,且研究者认为,炎性肠病患者神经系统的病变可能是重要的肠道外表现。目前利用磁共振成像对炎性肠病患者脑结构及功能的研究已取得初步的结果,因此,该文旨在综述炎性肠病相关的神经影像学研究领域目前的进展。

Inflammatory bowel disease is a kind of chronic and recurrent intestinal inflammatory disease with a tendency of lifelong recurrence, which has a variety etiologies. In addition to the known extraintestinal symptoms, such as arthritis and iritis, some studies have pointed out that inflammatory bowel disease patients also have nervous system involvement, and this may be another extraintestinal manifestation. Preliminary research findings have been obtained in the study of brain structure and function in patients with inflammatory bowel disease by using magnetic resonance imaging(MRI). Therefore, the purpose of this article is to review the current research progress in the field of neuroimaging of inflammatory bowel disease.