期刊文献+

急性呼吸窘迫综合征药物治疗的研究进展 被引量:5

Advances in pharmacological treatment for acute respiratory distress syndrome
原文传递
导出
摘要 急性呼吸窘迫综合征(ARDS)是常见的危重综合征,其发病率、病死率均较高,治疗措施包括呼吸支持和药物治疗.本文就糖皮质激素、他汀类药物、抗氧化剂、重组人活化蛋白C、镇静剂与肌松剂、外源性肺泡表面活性物质、间充质干细胞、扩血管药物等药物治疗ARDS的最新临床研究进展进行综述. Acute respiratory distress syndrome(ARDS)is a common critical syndrome with high morbidity and mortality.The treatments include respiratory support and drug therapy.In this paper,the latest clinical advances in the treatment of ARDS with glucocorticoids,statins,antioxidants,recombinant human activated protein C,sedatives and muscle relaxants,exogenous alveolar surfactants,mesenchymal stem cells,and vasodilators are reviewed.
作者 张可祥 周岐龙 刘超 Zhang Kexiang;Zhou Qilong;Liu Chao(Department of Critical Care Medicine,Three Gorges Center Hospital of Chongqing,Chongqing 404000,China)
出处 《中国基层医药》 CAS 2019年第21期2685-2688,共4页 Chinese Journal of Primary Medicine and Pharmacy
基金 重庆市万州区科学技术委员会科研项目(wzstc-042017072)。
关键词 呼吸窘迫综合征 成人 药物疗法 糖皮质激素类 西司他汀类 抗氧化剂 肺表面活性物质相关蛋白质类 间质干细胞 血管舒张药 综述 Respiratory distress syndrome adult Drug therapy Glucocorticoids Cystatins Antiox-idants Pulmonary surfactant-associated proteins Mesenchymal stem cells Vasodilator agents Review
  • 相关文献

参考文献6

二级参考文献50

  • 1吴禹,周向东.活性氧与肺炎性损伤[J].现代医药卫生,2005,21(1):31-32. 被引量:7
  • 2赵水平.他汀类药物抗炎防治动脉粥样硬化[J].中华医学杂志,2005,85(40):2818-2820. 被引量:19
  • 3肖晓辉,付明生,万毅新.槲皮素对百草枯致大鼠急性肺损伤治疗作用的实验研究[J].中国呼吸与危重监护杂志,2007,6(4):290-293. 被引量:4
  • 4Mosser DM,Edwards JP. Exploring the full spectrum ofmacrophage activation. Nat Rev Immunol, 2008, 8 : 958-969.
  • 5van der Meij E, Koning GG,Vriens PW, et al. A clinicalevaluation of statin pleiotropy : statins selectively and dose-dependentiy reduce vascular inflammation. PLoS One, 2013 , 8:e53882.
  • 6Pradel LC,Mitchell AJ,Zarubica A, et al. ATP-binding cassettetransporter hallmarks tissue macrophages and modulates cytokine-triggered polarization programs. Eur J Immunol, 2009 , 39 : 2270-2280.
  • 7Sica A,Mantovani A. Macrophage plasticity and polarization: invivo veritas. J Clin Invest, 2012,122:787-795.
  • 8Porcheray F, Viaud S, Rimaniol AC, et al. Macrophage activationswitching : an asset for the resolution of inflammation. Clin ExpImmunol, 2005,142:481*489.
  • 9Mantovani A, Garlanda C,Locati M. Macrophage diversity andpolarization in atherosclerosis : a question of balance. ArteriosclerThromb Vase Biol ,2009 , 29: 1419-1423.
  • 10Fujita E, Shimizu A, Masuda Y, et al. Statin attenuatesexperimental anti-glomerular basement membraneglomerulonephritis together with the augmentation of alternativelyactivated macrophages. Am J Pathol,2010, 177 : 1143-1154.

共引文献111

同被引文献31

引证文献5

二级引证文献48

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部