期刊文献+

诺斯清联合布地奈德鼻喷雾剂治疗变应性鼻炎80例疗效观察 被引量:6

下载PDF
导出
摘要 【目的】探讨诺斯清联合布地奈德鼻喷雾剂治疗变应性鼻炎的疗效.【方法】选取2016年1月至2018年1月本院耳鼻喉科收治的变应性鼻炎患者150例作为研究对象,按照不同治疗方案分为观察组(80例)和对照组(70例),对照组患者单纯使用布地奈德喷雾进行治疗,观察组患者在对照组基础上加用诺斯清.比较两组患者治疗后变应性鼻炎改善情况.【结果】观察组患者治疗总有效率显著高于对照组患者(P<0.05).治疗前,两组患者鼻部症状、眼部症状、非鼻部症状、行为问题、睡眠、日常活动、情感反应RQLQ评分比较,差异均无统计学意义(P>0.05);治疗两周后两组患者RQLQ评分均显著改善,且观察组患者评分下降程度优于对照组(P<0.05).两组患者治疗过程中不良反应发生率比较,差异无统计学意义(P>0.05).【结论】诺斯清联合布地奈德鼻喷雾剂治疗变应性鼻炎效果显著,可以改善患者临床症状,提高患者生活质量,值得临床上推广使用.
出处 《医学临床研究》 CAS 2019年第10期2045-2046,共2页 Journal of Clinical Research
  • 相关文献

参考文献4

二级参考文献52

  • 1罗玲.超声波鼻炎治疗仪治疗过敏性鼻炎的临床疗效[J].求医问药(下半月),2013(12):51-52. 被引量:4
  • 2郑红彬,绕雪燕,黄雪丽,等.中西医结合治疗过敏性鼻炎的临床效果观察[J].现代养生,2014(12):98.
  • 3Dosanjh A. Allergic rhinitis and childhood sleep disorder- ed breathing[J]. Allergol Immunopathol (Madr), 2009,37 (3) :171-172.
  • 4Zhang L, Han D, Huang D, et al. Prevalence of self-repor- ted allergic rhinitis in eleven major cities in China[J]. Int Arch Allergy Immunol, 2009,149 (1) : 47-57.
  • 5Lima SJ ,Pernambuco Lde A,Lins Ade L,et al. Jaw move- ment during the speech in children with allergic rhinitis [J]. CODAS, 2015,27(4) : 359-364.
  • 6Chen ML, Xu SH, Zhou PP, et al. Desloratadine citrate di- sodium in]ection,a potent histamine H-1 receptor antago- nist,inhibits chemokine production in ovalbumin-induced allergic rhinitis Guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and NF-kappa 13 signal cascades[J]. Eur J Pharmacol, 2015, 767(1) :98-107.
  • 7Johansson MW, Lye MH, BartheI SR, et al. Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes [J]. Am J Respir Cell Mol Biol,2004,31(4) :413-422.
  • 8Kyle J,Garton H, Gough M, et al. Stimulated shedding of vascular cell adhesion molecule 1 is mediated by'tumor necrosis factor-converting enzyme(Adam 17)[J]. J Biol Chemistry, 2003,278 (39) :37459-37464.
  • 9Cates CJ,Karner C.Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance),for chronic asthma in adults and children. Cochrane Database of Systematic Reviews . 2013
  • 10Vichyanond Pakit,Suratannon Chanthana,Lertbunnaphong Piyarat,Jirapongsananuruk Orathai,Visitsunthorn Nualanong.Clinical characteristics of children with non-allergic rhinitis vs with allergic rhinitis. Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand . 2011

同被引文献55

引证文献6

二级引证文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部