SWAT计划和MIROR项目介绍及其对循证中医药学发展的启示

Introduction on SWAT Programme and MIROR Programme and Their Enlightenment in the Development of Evidence-based Chinese Medicine

严格的随机对照试验是提供无偏倚证据的来源。由于目前国内外随机对照试验的设计、实施过程及结果报告方面存在诸多问题,在很大程度上降低了临床研究价值,造成经费浪费。因此,一些研究者意识到针对临床研究中存在的问题开展高质量的方法学研究,对提高临床研究水平有重要意义。在开展方法学研究方面,国外有嵌入式研究(Study Within A Trial,SWAT)和基于研究的研究(Research On Research,ROR),并形成了相应的组织。在该项研究中,研究者首先介绍了有一定影响力的SWAT计划和探索ROR研究方法的MIROR(Methods in Research on Research)项目进行介绍,并探讨其对循证中医药学发展的启示,以期引起相关研究者的重视。

Rigorous randomized controlled trials(RCTs)are the source of unbiased evidence.Due to problems in design,implementation and outcome reports of RCTs all over the world,the value of clinical study has been decreased and investment has been wasted to a large extent.Therefore,some researchers realize that high-quality methodological research aimed at the problems in clinical study is of great significance to improve the quality of clinical study.In terms of methodological research,there are study within a trial(SWAT)and research on research(ROR),and some organizations have been formed.Firstly,the influential SWAT programme and MIROR(Methods in Research on Research)programme,a programme that explores ROR research methods,is introduced in this study.Then their implications for the development of evidence-based Chinese medicine is discussed,so that relevant researchers may pay attention to this field.